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A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema.
Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, Tuder RM. Petrache I, et al. Among authors: medler tr. Am J Respir Crit Care Med. 2006 Jun 1;173(11):1222-8. doi: 10.1164/rccm.200512-1842OC. Epub 2006 Mar 2. Am J Respir Crit Care Med. 2006. PMID: 16514110 Free PMC article.
Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.
Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I. Medler TR, et al. Am J Respir Cell Mol Biol. 2008 Jun;38(6):639-46. doi: 10.1165/rcmb.2007-0274OC. Epub 2008 Jan 10. Am J Respir Cell Mol Biol. 2008. PMID: 18192502 Free PMC article.
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide.
Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, Berdyshev EV, Lungarella G, Tuder RM. Petrache I, et al. Among authors: medler tr. Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L44-53. doi: 10.1152/ajplung.00448.2007. Epub 2008 Apr 25. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18441093 Free PMC article.
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