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Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes.
Schrier RW, Estacio RO, Esler A, Mehler P. Schrier RW, et al. Kidney Int. 2002 Mar;61(3):1086-97. doi: 10.1046/j.1523-1755.2002.00213.x. Kidney Int. 2002. PMID: 11849464 Clinical Trial.
Although no difference was demonstrated in creatinine clearance (P = 0.43), a lower percentage of patients in the intensive group progressed from normoalbuminuria to microalbuminuria (P = 0.012) and microalbuminuria to overt albuminuria (P = 0.028). The inten …
Although no difference was demonstrated in creatinine clearance (P = 0.43), a lower percentage of patients in the intensive group pro …
Medical issues in treating renal transplant patients.
Kolpak S, Mehler P. Kolpak S, et al. Hosp Pract (1995). 2001 Jun 15;36(6):50-2, 55-6. doi: 10.3810/hp.2001.06.241. Hosp Pract (1995). 2001. PMID: 11419536
Intensive blood pressure control reduces the risk of cardiovascular events in patients with peripheral arterial disease and type 2 diabetes.
Mehler PS, Coll JR, Estacio R, Esler A, Schrier RW, Hiatt WR. Mehler PS, et al. Circulation. 2003 Feb 11;107(5):753-6. doi: 10.1161/01.cir.0000049640.46039.52. Circulation. 2003. PMID: 12578880 Clinical Trial.
In patients with PAD, there were 3 cardiovascular events (13.6%) on intensive treatment compared with 12 events (38.7%) on moderate treatment (P=0.046). After adjustment for multiple cardiovascular risk factors, an inverse relationship between ankle-brachial index and card …
In patients with PAD, there were 3 cardiovascular events (13.6%) on intensive treatment compared with 12 events (38.7%) on moderate treatmen …
Lack of improvement in the treatment of hyperlipidemia among patients with type 2 diabetes.
Mehler PS, Esler A, Estacio RO, MacKenzie TD, Hiatt WR, Schrier RW. Mehler PS, et al. Am J Med. 2003 Apr 1;114(5):377-82. doi: 10.1016/s0002-9343(02)01566-8. Am J Med. 2003. PMID: 12714127
RESULTS: The percentage of patients with a low-density lipoprotein (LDL) cholesterol level less than 130 mg/dL was 53% (n = 266) at baseline and 54% (n = 270) at the end of 5 years (P = 0.75). ...Only 19% (n = 25) of the 133 patients with known coronary artery disease had …
RESULTS: The percentage of patients with a low-density lipoprotein (LDL) cholesterol level less than 130 mg/dL was 53% (n = 266) at baseline …
Differential effects of antihypertensive agents on electrocardiographic voltage: results from the Appropriate Blood Pressure Control in Diabetes (ABCD) trial.
Havranek EP, Esler A, Estacio RO, Mehler PS, Schrier RW; Appropriate Blood Pressure Control in Diabetes Trial. Havranek EP, et al. Am Heart J. 2003 Jun;145(6):993-8. doi: 10.1016/S0002-8703(02)94780-0. Am Heart J. 2003. PMID: 12796754 Clinical Trial.
RESULTS: In 5 years of follow-up, the decline in adjusted Cornell voltage was significantly greater for patients treated with enalapril than for patients treated with nisoldipine (repeated measures analysis of variance P =.002). ...
RESULTS: In 5 years of follow-up, the decline in adjusted Cornell voltage was significantly greater for patients treated with enalapril than …
Albuminuria as a predictor of heart failure hospitalizations in patients with type 2 diabetes.
Hockensmith ML, Estacio RO, Mehler P, Havranek EP, Ecder ST, Lundgren RA, Schrier RW. Hockensmith ML, et al. J Card Fail. 2004 Apr;10(2):126-31. doi: 10.1016/j.cardfail.2003.09.003. J Card Fail. 2004. PMID: 15101024
RESULTS: Patients with overt albuminuria at baseline had a higher and earlier occurrence of HF hospitalizations than those with micro- or normoalbuminuria (13.6% versus 3.3%, odds ratio [OR]=3.1, 95% confidence interval [CI]=2.15-4.60, P<.0001). In the multiple logistic …
RESULTS: Patients with overt albuminuria at baseline had a higher and earlier occurrence of HF hospitalizations than those with micro- or no …
A community study of language concordance in Russian patients with diabetes.
Mehler PS, Lundgren RA, Pines I, Doll K. Mehler PS, et al. Ethn Dis. 2004 Autumn;14(4):584-8. Ethn Dis. 2004. PMID: 15724780
FINDINGS: Overall, the mean low density lipoprotein (LDL) level decreased by 20% from 126 mg/dL to 102 mg/dL (P=.0002) respectively before and after the Russian provider began treating these patients. Mean hemoglobin A1c decreased from 8.4% to 8.0% (P=.007), and dia …
FINDINGS: Overall, the mean low density lipoprotein (LDL) level decreased by 20% from 126 mg/dL to 102 mg/dL (P=.0002) respectively b …
Bridging the quality gap in diabetic hyperlipidemia: a practice-based intervention.
Mehler PS, Krantz MJ, Lundgren RA, Estacio RO, MacKenzie TD, Petralia L, Hiatt WR. Mehler PS, et al. Am J Med. 2005 Dec;118(12):1414. doi: 10.1016/j.amjmed.2005.07.038. Am J Med. 2005. PMID: 16378790 Clinical Trial.
RESULTS: Favorable provider actions increased significantly with the intervention (+22% compared with +6% in controls, P=.01). ...Lipid testing tended to increase to a greater extent at intervention sites (+23% for the combination of electronic and direct detailing vs +11% …
RESULTS: Favorable provider actions increased significantly with the intervention (+22% compared with +6% in controls, P=.01). ...Lip …
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