Mehta AB - Search Results

1

Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine.

Gerrard G, Payne E, Baker RJ, Jones DT, Potter M, Prentice HG, Ethell M, McCullough H, Burgess M, Mehta AB, Ganeshaguru K. Gerrard G, et al. Among authors: mehta ab. Haematologica. 2004 Jul;89(7):782-90. Haematologica. 2004. PMID: 15257929 Clinical Trial.

2

Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.

Ganeshaguru K, Wickremasinghe RG, Jones DT, Gordon M, Hart SM, Virchis AE, Prentice HG, Hoffbrand AV, Man A, Champain K, Csermak K, Mehta AB. Ganeshaguru K, et al. Among authors: mehta ab. Haematologica. 2002 Feb;87(2):167-76. Haematologica. 2002. PMID: 11836167

3

Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand.

Jones DT, Ganeshaguru K, Mitchell WA, Foroni L, Baker RJ, Prentice HG, Mehta AB, Wickremasinghe RG. Jones DT, et al. Among authors: mehta ab. Br J Haematol. 2003 Jun;121(5):713-20. doi: 10.1046/j.1365-2141.2003.04340.x. Br J Haematol. 2003. PMID: 12780785

4

A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C.

Virchis A, Ganeshaguru K, Hart S, Jones D, Fletcher L, Wright F, Wickremasinghe R, Man A, Csermak K, Meyer T, Fabbro D, Champain K, Yap A, Prentice HG, Mehta A. Virchis A, et al. Hematol J. 2002;3(3):131-6. doi: 10.1038/sj.thj.6200165. Hematol J. 2002. PMID: 12111648 Clinical Trial.

5

Fludarabine, cytosine arabinoside, granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes.

Virchis A, Koh M, Rankin P, Mehta A, Potter M, Hoffbrand AV, Prentice HG. Virchis A, et al. Br J Haematol. 2004 Jan;124(1):26-32. doi: 10.1046/j.1365-2141.2003.04728.x. Br J Haematol. 2004. PMID: 14675405 Clinical Trial.

6

Glucosylceramide synthase inhibitors sensitise CLL cells to cytotoxic agents without reversing P-gp functional activity.

Gerrard G, Butters TD, Ganeshaguru K, Mehta AB. Gerrard G, et al. Among authors: mehta ab. Eur J Pharmacol. 2009 May 1;609(1-3):34-9. doi: 10.1016/j.ejphar.2009.03.018. Epub 2009 Mar 12. Eur J Pharmacol. 2009. PMID: 19285492

7

Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis.

Jones DT, Ganeshaguru K, Anderson RJ, Jackson TR, Bruckdorfer KR, Low SY, Palmqvist L, Prentice HG, Hoffbrand AV, Mehta AB, Wickremasinghe RG. Jones DT, et al. Among authors: mehta ab. Blood. 2003 Apr 15;101(8):3174-80. doi: 10.1182/blood-2002-07-2143. Epub 2002 Dec 12. Blood. 2003. PMID: 12480711 Free article.

8

Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs.

Jones DT, Addison E, North JM, Lowdell MW, Hoffbrand AV, Mehta AB, Ganeshaguru K, Folarin NI, Wickremasinghe RG. Jones DT, et al. Among authors: mehta ab. Blood. 2004 Mar 1;103(5):1855-61. doi: 10.1182/blood-2003-05-1603. Epub 2003 Oct 23. Blood. 2004. PMID: 14576064 Free article.

9

The impact of dose escalation and resistance modulation in older patients with acute myeloid leukaemia and high risk myelodysplastic syndrome: the results of the LRF AML14 trial.

Burnett AK, Milligan D, Goldstone A, Prentice A, McMullin MF, Dennis M, Sellwood E, Pallis M, Russell N, Hills RK, Wheatley K; United Kingdom National Cancer Research Institute Haematological Oncology Study Group. Burnett AK, et al. Br J Haematol. 2009 May;145(3):318-32. doi: 10.1111/j.1365-2141.2009.07604.x. Epub 2009 Mar 8. Br J Haematol. 2009. PMID: 19291085 Clinical Trial.

10

Mycophenolate mofetil for the treatment of refractory auto-immune haemolytic anaemia and auto-immune thrombocytopenia purpura.

Howard J, Hoffbrand AV, Prentice HG, Mehta A. Howard J, et al. Br J Haematol. 2002 Jun;117(3):712-5. doi: 10.1046/j.1365-2141.2002.03430.x. Br J Haematol. 2002. PMID: 12028047

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