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Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation.
Saarentaus EC, Karjalainen J, Rämö JT, Kiiskinen T, Havulinna AS, Mehtonen J, Hautakangas H, Ruotsalainen S, Tamlander M, Mars N; FINNGEN; Toppila-Salmi S, Pirinen M, Kurki M, Ripatti S, Daly M, Palotie T, Mäkitie A, Palotie A. Saarentaus EC, et al. Among authors: mehtonen j. Nat Commun. 2023 Jan 18;14(1):83. doi: 10.1038/s41467-022-33626-w. Nat Commun. 2023. PMID: 36653354 Free PMC article.
Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases.
Kiiskinen T, Helkkula P, Krebs K, Karjalainen J, Saarentaus E, Mars N, Lehisto A, Zhou W, Cordioli M, Jukarainen S, Rämö JT, Mehtonen J, Veerapen K, Räsänen M, Ruotsalainen S, Maasha M; FinnGen; Niiranen T, Tuomi T, Salomaa V, Kurki M, Pirinen M, Palotie A, Daly M, Ganna A, Havulinna AS, Milani L, Ripatti S. Kiiskinen T, et al. Among authors: mehtonen j. Nat Med. 2023 Jan;29(1):209-218. doi: 10.1038/s41591-022-02122-5. Epub 2023 Jan 18. Nat Med. 2023. PMID: 36653479 Free PMC article.
Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.
Grönroos T, Teppo S, Mehtonen J, Laukkanen S, Liuksiala T, Nykter M, Heinäniemi M, Lohi O. Grönroos T, et al. Among authors: mehtonen j. Leuk Res. 2017 Mar;54:1-6. doi: 10.1016/j.leukres.2016.12.005. Epub 2016 Dec 26. Leuk Res. 2017. PMID: 28063378
In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.
Laukkanen S, Grönroos T, Pölönen P, Kuusanmäki H, Mehtonen J, Cloos J, Ossenkoppele G, Gjertsen B, Øystein B, Heckman C, Heinäniemi M, Kontro M, Lohi O. Laukkanen S, et al. Among authors: mehtonen j. Blood Cancer J. 2017 Sep 8;7(9):e604. doi: 10.1038/bcj.2017.87. Blood Cancer J. 2017. PMID: 28885610 Free PMC article. No abstract available.
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.
Bouvy-Liivrand M, Hernández de Sande A, Pölönen P, Mehtonen J, Vuorenmaa T, Niskanen H, Sinkkonen L, Kaikkonen MU, Heinäniemi M. Bouvy-Liivrand M, et al. Among authors: mehtonen j. Nucleic Acids Res. 2017 Nov 16;45(20):12054. doi: 10.1093/nar/gkx909. Nucleic Acids Res. 2017. PMID: 29036333 Free PMC article. No abstract available.
Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.
Pölönen P, Mehtonen J, Lin J, Liuksiala T, Häyrynen S, Teppo S, Mäkinen A, Kumar A, Malani D, Pohjolainen V, Porkka K, Heckman CA, May P, Hautamäki V, Granberg KJ, Lohi O, Nykter M, Heinäniemi M. Pölönen P, et al. Among authors: mehtonen j. Cancer Res. 2019 May 15;79(10):2466-2479. doi: 10.1158/0008-5472.CAN-18-2970. Epub 2019 Apr 2. Cancer Res. 2019. PMID: 30940663
44 results