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Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines.
Wu Y, Lu J, Antony S, Juhasz A, Liu H, Jiang G, Meitzler JL, Hollingshead M, Haines DC, Butcher D, Roy K, Doroshow JH. Wu Y, et al. J Immunol. 2013 Feb 15;190(4):1859-72. doi: 10.4049/jimmunol.1201725. Epub 2013 Jan 7. J Immunol. 2013. PMID: 23296709 Free PMC article.
Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.
Meitzler JL, Hinde S, Bánfi B, Nauseef WM, Ortiz de Montellano PR. Meitzler JL, et al. J Biol Chem. 2013 Mar 8;288(10):7147-57. doi: 10.1074/jbc.M112.414797. Epub 2013 Jan 28. J Biol Chem. 2013. PMID: 23362256 Free PMC article.
Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody.
Wu Y, Antony S, Hewitt SM, Jiang G, Yang SX, Meitzler JL, Juhasz A, Lu J, Liu H, Doroshow JH, Roy K. Wu Y, et al. Int J Oncol. 2013 Apr;42(4):1229-38. doi: 10.3892/ijo.2013.1821. Epub 2013 Feb 11. Int J Oncol. 2013. PMID: 23404210 Free PMC article.
NADPH oxidases: a perspective on reactive oxygen species production in tumor biology.
Meitzler JL, Antony S, Wu Y, Juhasz A, Liu H, Jiang G, Lu J, Roy K, Doroshow JH. Meitzler JL, et al. Antioxid Redox Signal. 2014 Jun 10;20(17):2873-89. doi: 10.1089/ars.2013.5603. Epub 2013 Oct 24. Antioxid Redox Signal. 2014. PMID: 24156355 Free PMC article. Review.
NADPH oxidases and cancer.
Roy K, Wu Y, Meitzler JL, Juhasz A, Liu H, Jiang G, Lu J, Antony S, Doroshow JH. Roy K, et al. Clin Sci (Lond). 2015 Jun;128(12):863-75. doi: 10.1042/CS20140542. Clin Sci (Lond). 2015. PMID: 25818486 Review.
Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A.
Wu Y, Meitzler JL, Antony S, Juhasz A, Lu J, Jiang G, Liu H, Hollingshead M, Haines DC, Butcher D, Panter MS, Roy K, Doroshow JH. Wu Y, et al. Oncotarget. 2016 Oct 18;7(42):68412-68433. doi: 10.18632/oncotarget.12032. Oncotarget. 2016. PMID: 27637085 Free PMC article.
Decoding NADPH oxidase 4 expression in human tumors.
Meitzler JL, Makhlouf HR, Antony S, Wu Y, Butcher D, Jiang G, Juhasz A, Lu J, Dahan I, Jansen-Dürr P, Pircher H, Shah AM, Roy K, Doroshow JH. Meitzler JL, et al. Redox Biol. 2017 Oct;13:182-195. doi: 10.1016/j.redox.2017.05.016. Epub 2017 May 26. Redox Biol. 2017. PMID: 28578276 Free PMC article.
Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases.
Lu J, Risbood P, Kane CT Jr, Hossain MT, Anderson L, Hill K, Monks A, Wu Y, Antony S, Juhasz A, Liu H, Jiang G, Harris E, Roy K, Meitzler JL, Konaté M, Doroshow JH. Lu J, et al. Among authors: meitzler jl. Biochem Pharmacol. 2017 Nov 1;143:25-38. doi: 10.1016/j.bcp.2017.07.007. Epub 2017 Jul 11. Biochem Pharmacol. 2017. PMID: 28709950 Free PMC article.
Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR.
Diebold BA, Wilder SG, De Deken X, Meitzler JL, Doroshow JH, McCoy JW, Zhu Y, Lambeth JD. Diebold BA, et al. Among authors: meitzler jl. Methods Mol Biol. 2019;1982:191-229. doi: 10.1007/978-1-4939-9424-3_12. Methods Mol Biol. 2019. PMID: 31172474
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