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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1959 1
1960 5
1961 5
1962 1
1963 7
1964 19
1965 25
1966 23
1967 32
1968 52
1969 46
1970 52
1971 71
1972 59
1973 59
1974 71
1975 87
1976 102
1977 90
1978 116
1979 153
1980 131
1981 138
1982 174
1983 162
1984 186
1985 247
1986 261
1987 249
1988 314
1989 324
1990 344
1991 369
1992 384
1993 397
1994 413
1995 466
1996 529
1997 614
1998 652
1999 725
2000 653
2001 722
2002 724
2003 752
2004 654
2005 799
2006 865
2007 811
2008 837
2009 869
2010 932
2011 965
2012 1036
2013 1074
2014 1215
2015 1199
2016 1207
2017 1316
2018 1410
2019 1560
2020 1840
2021 1945
2022 2064
2023 1929
2024 842

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33,163 results

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Page 1
Circadian Rhythm Dysregulation and Restoration: The Role of Melatonin.
Vasey C, McBride J, Penta K. Vasey C, et al. Nutrients. 2021 Sep 30;13(10):3480. doi: 10.3390/nu13103480. Nutrients. 2021. PMID: 34684482 Free PMC article. Review.
Previous studies have postulated that dysregulation of melatonin rhythms is the driving force behind sleep and circadian disorders. ...We explored the mechanisms behind melatonin dysregulation and how it affects various disorders. Additionally, we examined associate …
Previous studies have postulated that dysregulation of melatonin rhythms is the driving force behind sleep and circadian disorders. . …
Melatonin: Physiological effects in humans.
Claustrat B, Leston J. Claustrat B, et al. Neurochirurgie. 2015 Apr-Jun;61(2-3):77-84. doi: 10.1016/j.neuchi.2015.03.002. Epub 2015 Apr 20. Neurochirurgie. 2015. PMID: 25908646 Review.
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at night under normal light/dark conditions. ...Since the regulating system of melatonin secretion is complex, following central and autonomic pathways, there are many pathophysiol
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at night under normal light/dark conditions. ..
Melatonin: exceeding expectations.
Reiter RJ, Tan DX, Galano A. Reiter RJ, et al. Physiology (Bethesda). 2014 Sep;29(5):325-33. doi: 10.1152/physiol.00011.2014. Physiology (Bethesda). 2014. PMID: 25180262 Free article. Review.
Receptor-dependent functions include circadian rhythm regulation, sleep, and cancer inhibition. The receptor-independent actions relate to melatonin's ability to function in the detoxification of free radicals, thereby protecting critical molecules from the destruct …
Receptor-dependent functions include circadian rhythm regulation, sleep, and cancer inhibition. The receptor-independent actions relate to …
Melatonin and its ubiquitous anticancer effects.
Bhattacharya S, Patel KK, Dehari D, Agrawal AK, Singh S. Bhattacharya S, et al. Mol Cell Biochem. 2019 Dec;462(1-2):133-155. doi: 10.1007/s11010-019-03617-5. Epub 2019 Aug 26. Mol Cell Biochem. 2019. PMID: 31451998 Review.
Apart from circadian regulations, Melatonin also has antioxidant, anti-ageing, immunomodulation and anticancer properties. ...This review precisely emphasizes the anticancer effect of Melatonin on various cancer cells. This review exemplifies the epidemiology and an …
Apart from circadian regulations, Melatonin also has antioxidant, anti-ageing, immunomodulation and anticancer properties. ...This re …
Melatonin: A novel candidate for the treatment of osteoarthritis.
Zhang Y, Liu T, Yang H, He F, Zhu X. Zhang Y, et al. Ageing Res Rev. 2022 Jun;78:101635. doi: 10.1016/j.arr.2022.101635. Epub 2022 Apr 25. Ageing Res Rev. 2022. PMID: 35483626 Review.
Findings from preliminary application of melatonin or melatonin-loaded biomaterials in animal models have affirmed its potential anti-arthritic effects. Herein, we summarize the anti-arthritic effects of melatonin on OA cartilage and demonstrate that melat
Findings from preliminary application of melatonin or melatonin-loaded biomaterials in animal models have affirmed its potenti …
Melatonin as an antioxidant: under promises but over delivers.
Reiter RJ, Mayo JC, Tan DX, Sainz RM, Alatorre-Jimenez M, Qin L. Reiter RJ, et al. J Pineal Res. 2016 Oct;61(3):253-78. doi: 10.1111/jpi.12360. Epub 2016 Sep 1. J Pineal Res. 2016. PMID: 27500468 Review.
Melatonin's ubiquitous but unequal intracellular distribution, including its high concentrations in mitochondria, likely aid in its capacity to resist oxidative stress and cellular apoptosis. ...Melatonin's capacity to prevent oxidative damage and the
Melatonin's ubiquitous but unequal intracellular distribution, including its high concentrations in mitochondria, likely aid i
Melatonin's Impact on Antioxidative and Anti-Inflammatory Reprogramming in Homeostasis and Disease.
Chitimus DM, Popescu MR, Voiculescu SE, Panaitescu AM, Pavel B, Zagrean L, Zagrean AM. Chitimus DM, et al. Biomolecules. 2020 Aug 20;10(9):1211. doi: 10.3390/biom10091211. Biomolecules. 2020. PMID: 32825327 Free PMC article. Review.
Melatonin promotes adaptation through allostasis and stands out as an endogenous, dietary, and therapeutic molecule with important health benefits. ...In addition, there might be an emerging role for melatonin as an adjuvant in treating coronavirus disease 2019 (COV
Melatonin promotes adaptation through allostasis and stands out as an endogenous, dietary, and therapeutic molecule with important he
Melatonin and its relationship to plant hormones.
Arnao MB, Hernández-Ruiz J. Arnao MB, et al. Ann Bot. 2018 Feb 12;121(2):195-207. doi: 10.1093/aob/mcx114. Ann Bot. 2018. PMID: 29069281 Free PMC article. Review.
The effects that some melatonin treatments have on endogenous plant hormone levels, their related genes (biosynthesis, catabolism, receptors and transcription factors) and the physiological actions induced by melatonin, mainly in stress conditions, are discussed. .. …
The effects that some melatonin treatments have on endogenous plant hormone levels, their related genes (biosynthesis, catabolism, re …
Melatonin and Female Reproduction: An Expanding Universe.
Olcese JM. Olcese JM. Front Endocrinol (Lausanne). 2020 Mar 6;11:85. doi: 10.3389/fendo.2020.00085. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32210911 Free PMC article. Review.
For more than a half century the hormone melatonin has been associated with vertebrate reproduction, particularly in the context of seasonal breeding. ...A vast literature on melatonin and vertebrate biology has accrued over the past 60 years since melatonin' …
For more than a half century the hormone melatonin has been associated with vertebrate reproduction, particularly in the context of s …
Melatonin as a Potential Approach to Anxiety Treatment.
Repova K, Baka T, Krajcirovicova K, Stanko P, Aziriova S, Reiter RJ, Simko F. Repova K, et al. Int J Mol Sci. 2022 Dec 19;23(24):16187. doi: 10.3390/ijms232416187. Int J Mol Sci. 2022. PMID: 36555831 Free PMC article. Review.
The underlying pathomechanism of melatonin's benefit in anxiety may reside in its sympatholytic action, interaction with the renin-angiotensin and glucocorticoid systems, modulation of interneuronal signaling and its extraordinary antioxidant and radical scavenging …
The underlying pathomechanism of melatonin's benefit in anxiety may reside in its sympatholytic action, interaction with the r …
33,163 results
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