Melendez V - Search Results

1

Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives.

Shiraki H, Kozar MP, Melendez V, Hudson TH, Ohrt C, Magill AJ, Lin AJ. Shiraki H, et al. Among authors: melendez v. J Med Chem. 2011 Jan 13;54(1):131-42. doi: 10.1021/jm100911f. Epub 2010 Dec 8. J Med Chem. 2011. PMID: 21141892

2

New imidazolidinedione derivatives as antimalarial agents.

Zhang L, Sathunuru R, Luong T, Melendez V, Kozar MP, Lin AJ. Zhang L, et al. Among authors: melendez v. Bioorg Med Chem. 2011 Feb 15;19(4):1541-9. doi: 10.1016/j.bmc.2010.12.028. Epub 2010 Dec 16. Bioorg Med Chem. 2011. PMID: 21282058

3

Synthesis and antimalarial activity of 2-guanidino-4-oxoimidazoline derivatives.

Liu X, Wang X, Li Q, Kozar MP, Melendez V, O'Neil MT, Lin AJ. Liu X, et al. Among authors: melendez v. J Med Chem. 2011 Jul 14;54(13):4523-35. doi: 10.1021/jm200111g. Epub 2011 May 31. J Med Chem. 2011. PMID: 21627120

4

Structure-activity relationships of 4-position diamine quinoline methanols as intermittent preventative treatment (IPT) against Plasmodium falciparum.

Milner E, Gardner S, Moon J, Grauer K, Auschwitz J, Bathurst I, Caridha D, Gerena L, Gettayacamin M, Johnson J, Kozar M, Lee P, Leed S, Li Q, McCalmont W, Melendez V, Roncal N, Sciotti R, Smith B, Sousa J, Tungtaeng A, Wipf P, Dow G. Milner E, et al. Among authors: melendez v. J Med Chem. 2011 Sep 22;54(18):6277-85. doi: 10.1021/jm200647u. Epub 2011 Aug 22. J Med Chem. 2011. PMID: 21854078

5

Review: Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations.

Myint HY, Berman J, Walker L, Pybus B, Melendez V, Baird JK, Ohrt C. Myint HY, et al. Among authors: melendez v. Am J Trop Med Hyg. 2011 Dec;85(6):1010-4. doi: 10.4269/ajtmh.2011.11-0498. Am J Trop Med Hyg. 2011. PMID: 22144436 Free PMC article. Review.

6

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy.

Milner E, Sousa J, Pybus B, Auschwitz J, Caridha D, Gardner S, Grauer K, Harris E, Hickman M, Kozar MP, Lee P, Leed S, Li Q, Melendez V, Moon J, Ngundam F, O'Neil M, Parriott S, Potter B, Sciotti R, Tangteung A, Dow GS. Milner E, et al. Among authors: melendez v. Eur J Drug Metab Pharmacokinet. 2012 Mar;37(1):17-22. doi: 10.1007/s13318-012-0080-2. Eur J Drug Metab Pharmacokinet. 2012. PMID: 22314893

7

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Pybus BS, Sousa JC, Jin X, Ferguson JA, Christian RE, Barnhart R, Vuong C, Sciotti RJ, Reichard GA, Kozar MP, Walker LA, Ohrt C, Melendez V. Pybus BS, et al. Among authors: melendez v. Malar J. 2012 Aug 2;11:259. doi: 10.1186/1475-2875-11-259. Malar J. 2012. PMID: 22856549 Free PMC article.

8

Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice.

Wang H, Li Q, Reyes S, Zhang J, Zeng Q, Zhang P, Xie L, Lee PJ, Roncal N, Melendez V, Hickman M, Kozar MP. Wang H, et al. Among authors: melendez v. Nanomedicine. 2014 Jan;10(1):57-65. doi: 10.1016/j.nano.2013.07.010. Epub 2013 Jul 25. Nanomedicine. 2014. PMID: 23891618

9

In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones.

Gutteridge CE, Thota DS, Curtis SM, Kozar MP, Li Q, Xie L, Zhang J, Melendez V, Asher CO, Luong TT, Gerena L, Nichols DA, Montip G. Gutteridge CE, et al. Among authors: melendez v. Pharmacology. 2011;87(1-2):96-104. doi: 10.1159/000322532. Epub 2011 Feb 1. Pharmacology. 2011. PMID: 21282967

10

Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum.

Milner E, Sousa J, Pybus B, Melendez V, Gardner S, Grauer K, Moon J, Carroll D, Auschwitz J, Gettayacamin M, Lee P, Leed S, McCalmont W, Norval S, Tungtaeng A, Zeng Q, Kozar M, Read KD, Li Q, Dow G. Milner E, et al. Among authors: melendez v. Eur J Drug Metab Pharmacokinet. 2011 Sep;36(3):151-8. doi: 10.1007/s13318-011-0047-8. Epub 2011 Jul 13. Eur J Drug Metab Pharmacokinet. 2011. PMID: 21751074

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