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Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation.
Mellado M, Rodríguez-Frade JM, Mañes S, Martínez-A C. Mellado M, et al. Annu Rev Immunol. 2001;19:397-421. doi: 10.1146/annurev.immunol.19.1.397. Annu Rev Immunol. 2001. PMID: 11244042 Review.
Enterotoxin septic shock protection and deficient T helper 2 cytokine production in growth hormone transgenic mice.
Gonzalo JA, Mazuchelli R, Mellado M, Frade JM, Carrera AC, von Kobbe C, Merida I, Martinez-A C. Gonzalo JA, et al. Among authors: mellado m. J Immunol. 1996 Oct 15;157(8):3298-304. J Immunol. 1996. PMID: 8871624
Conformational changes required in the human growth hormone receptor for growth hormone signaling.
Mellado M, Rodríguez-Frade JM, Kremer L, von Kobbe C, de Ana AM, Mérida I, Martinez-A C. Mellado M, et al. J Biol Chem. 1997 Apr 4;272(14):9189-96. doi: 10.1074/jbc.272.14.9189. J Biol Chem. 1997. PMID: 9083050
Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis.
Nieto M, Frade JM, Sancho D, Mellado M, Martinez-A C, Sánchez-Madrid F. Nieto M, et al. Among authors: mellado m. J Exp Med. 1997 Jul 7;186(1):153-8. doi: 10.1084/jem.186.1.153. J Exp Med. 1997. PMID: 9207004 Free PMC article.
The amino-terminal domain of the CCR2 chemokine receptor acts as coreceptor for HIV-1 infection.
Frade JM, Llorente M, Mellado M, Alcamí J, Gutiérrez-Ramos JC, Zaballos A, Real G, Martínez-A C. Frade JM, et al. Among authors: mellado m. J Clin Invest. 1997 Aug 1;100(3):497-502. doi: 10.1172/JCI119558. J Clin Invest. 1997. PMID: 9239395 Free PMC article.
Finally, a set of mAb specific for the CCR2 amino-terminal domain, one of which mimics MCP-1 activity, has a potent suppressive effect on HIV-1 replication in M- and T-tropic HIV-1 viral isolates. ...
Finally, a set of mAb specific for the CCR2 amino-terminal domain, one of which mimics MCP-1 activity, has a potent suppressive effect on HI …
Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2.
Aragay AM, Mellado M, Frade JM, Martin AM, Jimenez-Sainz MC, Martinez-A C, Mayor F Jr. Aragay AM, et al. Among authors: mellado m. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2985-90. doi: 10.1073/pnas.95.6.2985. Proc Natl Acad Sci U S A. 1998. PMID: 9501202 Free PMC article.
Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells.
Frade JM, Mellado M, del Real G, Gutierrez-Ramos JC, Lind P, Martinez-A C. Frade JM, et al. Among authors: mellado m. J Immunol. 1997 Dec 1;159(11):5576-84. J Immunol. 1997. PMID: 9548499
The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.
Mellado M, Rodríguez-Frade JM, Aragay A, del Real G, Martín AM, Vila-Coro AJ, Serrano A, Mayor F Jr, Martínez-A C. Mellado M, et al. J Immunol. 1998 Jul 15;161(2):805-13. J Immunol. 1998. PMID: 9670957
The chemokines are a growing family of low m.w., 70- to 80-residue proinflammatory cytokines that operate by interacting with G protein-coupled receptors. ...
The chemokines are a growing family of low m.w., 70- to 80-residue proinflammatory cytokines that operate by interacting with G prote …
The chemokine SDF-1alpha triggers a chemotactic response and induces cell polarization in human B lymphocytes.
Vicente-Manzanares M, Montoya MC, Mellado M, Frade JM, del Pozo MA, Nieto M, de Landazuri MO, Martínez-A C, Sánchez-Madrid F. Vicente-Manzanares M, et al. Among authors: mellado m. Eur J Immunol. 1998 Jul;28(7):2197-207. doi: 10.1002/(SICI)1521-4141(199807)28:07<2197::AID-IMMU2197>3.0.CO;2-F. Eur J Immunol. 1998. PMID: 9692889
Roles of chemokines and receptor polarization in NK-target cell interactions.
Nieto M, Navarro F, Perez-Villar JJ, del Pozo MA, González-Amaro R, Mellado M, Frade JM, Martínez-A C, López-Botet M, Sánchez-Madrid F. Nieto M, et al. Among authors: mellado m. J Immunol. 1998 Oct 1;161(7):3330-9. J Immunol. 1998. PMID: 9759849
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