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Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials.
Lipton A, Theriault RL, Hortobagyi GN, Simeone J, Knight RD, Mellars K, Reitsma DJ, Heffernan M, Seaman JJ. Lipton A, et al. Among authors: mellars k. Cancer. 2000 Mar 1;88(5):1082-90. doi: 10.1002/(sici)1097-0142(20000301)88:5<1082::aid-cncr20>3.0.co;2-z. Cancer. 2000. PMID: 10699899 Clinical Trial.
Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate. Protocol 19 Aredia Breast Cancer Study Group.
Hortobagyi GN, Theriault RL, Lipton A, Porter L, Blayney D, Sinoff C, Wheeler H, Simeone JF, Seaman JJ, Knight RD, Heffernan M, Mellars K, Reitsma DJ. Hortobagyi GN, et al. Among authors: mellars k. J Clin Oncol. 1998 Jun;16(6):2038-44. doi: 10.1200/JCO.1998.16.6.2038. J Clin Oncol. 1998. PMID: 9626201 Clinical Trial.
Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group.
Theriault RL, Lipton A, Hortobagyi GN, Leff R, Glück S, Stewart JF, Costello S, Kennedy I, Simeone J, Seaman JJ, Knight RD, Mellars K, Heffernan M, Reitsma DJ. Theriault RL, et al. Among authors: mellars k. J Clin Oncol. 1999 Mar;17(3):846-54. doi: 10.1200/JCO.1999.17.3.846. J Clin Oncol. 1999. PMID: 10071275 Clinical Trial.