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CZH proteins: a new family of Rho-GEFs.
Meller N, Merlot S, Guda C. Meller N, et al. J Cell Sci. 2005 Nov 1;118(Pt 21):4937-46. doi: 10.1242/jcs.02671. J Cell Sci. 2005. PMID: 16254241 Review.
In vivo dynamics of Rac-membrane interactions.
Moissoglu K, Slepchenko BM, Meller N, Horwitz AF, Schwartz MA. Moissoglu K, et al. Mol Biol Cell. 2006 Jun;17(6):2770-9. doi: 10.1091/mbc.e06-01-0005. Epub 2006 Apr 5. Mol Biol Cell. 2006. PMID: 16597700 Free PMC article.
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins.
Meller N, Irani-Tehrani M, Kiosses WB, Del Pozo MA, Schwartz MA. Meller N, et al. Nat Cell Biol. 2002 Sep;4(9):639-47. doi: 10.1038/ncb835. Nat Cell Biol. 2002. PMID: 12172552
Function of the N-terminus of zizimin1: autoinhibition and membrane targeting.
Meller N, Westbrook MJ, Shannon JD, Guda C, Schwartz MA. Meller N, et al. Biochem J. 2008 Jan 15;409(2):525-33. doi: 10.1042/BJ20071263. Biochem J. 2008. PMID: 17935486 Free PMC article.
We demonstrate that the N-terminal half binds to the GEF domain through three distinct areas, including the CZH1, to inhibit the interaction with Cdc42. The N-terminal PH (pleckstrin homology) domain binds phosphoinositides and mediates zizimin1 membrane targeting. …
We demonstrate that the N-terminal half binds to the GEF domain through three distinct areas, including the CZH1, to inhibit the inte …
Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.
Nishikimi A, Meller N, Uekawa N, Isobe K, Schwartz MA, Maruyama M. Nishikimi A, et al. FEBS Lett. 2005 Feb 14;579(5):1039-46. doi: 10.1016/j.febslet.2005.01.006. Epub 2005 Jan 13. FEBS Lett. 2005. PMID: 15710388
Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans.
Doran AC, Lehtinen AB, Meller N, Lipinski MJ, Slayton RP, Oldham SN, Skaflen MD, Yeboah J, Rich SS, Bowden DW, McNamara CA. Doran AC, et al. Among authors: meller n. Circ Res. 2010 Apr 16;106(7):1303-11. doi: 10.1161/CIRCRESAHA.109.210294. Epub 2010 Feb 25. Circ Res. 2010. PMID: 20185798 Free PMC article.
Emergence and subsequent functional specialization of kindlins during evolution of cell adhesiveness.
Meller J, Rogozin IB, Poliakov E, Meller N, Bedanov-Pack M, Plow EF, Qin J, Podrez EA, Byzova TV. Meller J, et al. Among authors: meller n. Mol Biol Cell. 2015 Feb 15;26(4):786-96. doi: 10.1091/mbc.E14-08-1294. Epub 2014 Dec 24. Mol Biol Cell. 2015. PMID: 25540429 Free PMC article.
Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function.
Meller N, Liu YC, Collins TL, Bonnefoy-Bérard N, Baier G, Isakov N, Altman A. Meller N, et al. Mol Cell Biol. 1996 Oct;16(10):5782-91. doi: 10.1128/mcb.16.10.5782. Mol Cell Biol. 1996. PMID: 8816492 Free PMC article.
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