Mellert H - Search Results

1

MYST protein acetyltransferase activity requires active site lysine autoacetylation.

Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, Thibault P, Verreault A, Johnson FB, Berger SL, Sternglanz R, McMahon SB, Côté J, Marmorstein R. Yuan H, et al. Among authors: mellert h. EMBO J. 2012 Jan 4;31(1):58-70. doi: 10.1038/emboj.2011.382. Epub 2011 Oct 21. EMBO J. 2012. PMID: 22020126 Free PMC article.

2

Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells.

Mellert HS, McMahon SB. Mellert HS, et al. Trends Biochem Sci. 2009 Nov;34(11):571-8. doi: 10.1016/j.tibs.2009.06.010. Epub 2009 Oct 12. Trends Biochem Sci. 2009. PMID: 19819149 Free PMC article. Review.

3

hMOF, a KAT(8) with many lives.

Mellert HS, McMahon SB. Mellert HS, et al. Mol Cell. 2009 Oct 23;36(2):174-5. doi: 10.1016/j.molcel.2009.10.005. Mol Cell. 2009. PMID: 19854127 Free article.

4

The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain.

Mellert H, Sykes SM, Murphy ME, McMahon SB. Mellert H, et al. Cell Cycle. 2007 Jun 1;6(11):1304-6. doi: 10.4161/cc.6.11.4343. Epub 2007 Jun 24. Cell Cycle. 2007. PMID: 17534149 Review.

5

Acetylation of the p53 DNA-binding domain regulates apoptosis induction.

Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS, McMahon SB. Sykes SM, et al. Mol Cell. 2006 Dec 28;24(6):841-51. doi: 10.1016/j.molcel.2006.11.026. Mol Cell. 2006. PMID: 17189187 Free PMC article.

6

Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis.

Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ 3rd, Schultz DC, McMahon SB. Mellert HS, et al. J Biol Chem. 2011 Feb 11;286(6):4264-70. doi: 10.1074/jbc.M110.184663. Epub 2010 Dec 9. J Biol Chem. 2011. PMID: 21148320 Free PMC article.

7

A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.

Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB. Monteith JA, et al. Among authors: mellert h. Mol Oncol. 2016 Oct;10(8):1207-20. doi: 10.1016/j.molonc.2016.05.007. Epub 2016 Jun 7. Mol Oncol. 2016. PMID: 27341992 Free PMC article.

8

Regulation of microRNA-145 by growth arrest and differentiation.

La Rocca G, Shi B, Audia A, Ferrari-Amorotti G, Mellert HS, Calabretta B, McMahon SB, Sepp-Lorenzino L, Baserga R. La Rocca G, et al. Exp Cell Res. 2011 Feb 15;317(4):488-95. doi: 10.1016/j.yexcr.2010.11.010. Epub 2010 Nov 25. Exp Cell Res. 2011. PMID: 21111732

9

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.

Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Aggarwal P, et al. Among authors: mellert h. Cancer Cell. 2010 Oct 19;18(4):329-40. doi: 10.1016/j.ccr.2010.08.012. Cancer Cell. 2010. PMID: 20951943 Free PMC article.

10

Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC.

Zhang XY, Pfeiffer HK, Mellert HS, Stanek TJ, Sussman RT, Kumari A, Yu D, Rigoutsos I, Thomas-Tikhonenko A, Seidel HE, Chodosh LA, Packham G, Baserga R, McMahon SB. Zhang XY, et al. Mol Cell Biol. 2011 Dec;31(24):5037-45. doi: 10.1128/MCB.06297-11. Epub 2011 Oct 10. Mol Cell Biol. 2011. PMID: 21986497 Free PMC article.

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