Mellody KT - Search Results

1

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression.

Shimoda M, Mellody KT, Orimo A. Shimoda M, et al. Among authors: mellody kt. Semin Cell Dev Biol. 2010 Feb;21(1):19-25. doi: 10.1016/j.semcdb.2009.10.002. Epub 2009 Oct 24. Semin Cell Dev Biol. 2010. PMID: 19857592 Free PMC article. Review.

2

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts.

Kojima Y, Acar A, Eaton EN, Mellody KT, Scheel C, Ben-Porath I, Onder TT, Wang ZC, Richardson AL, Weinberg RA, Orimo A. Kojima Y, et al. Among authors: mellody kt. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20009-14. doi: 10.1073/pnas.1013805107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041659 Free PMC article.

3

Nanostructure of fibrillin-1 reveals compact conformation of EGF arrays and mechanism for extensibility.

Baldock C, Siegler V, Bax DV, Cain SA, Mellody KT, Marson A, Haston JL, Berry R, Wang MC, Grossmann JG, Roessle M, Kielty CM, Wess TJ. Baldock C, et al. Among authors: mellody kt. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11922-7. doi: 10.1073/pnas.0601609103. Epub 2006 Jul 31. Proc Natl Acad Sci U S A. 2006. PMID: 16880403 Free PMC article.

4

Molecular basis of elastic fiber formation. Critical interactions and a tropoelastin-fibrillin-1 cross-link.

Rock MJ, Cain SA, Freeman LJ, Morgan A, Mellody K, Marson A, Shuttleworth CA, Weiss AS, Kielty CM. Rock MJ, et al. J Biol Chem. 2004 May 28;279(22):23748-58. doi: 10.1074/jbc.M400212200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15039439 Free article.

5

Homotypic fibrillin-1 interactions in microfibril assembly.

Marson A, Rock MJ, Cain SA, Freeman LJ, Morgan A, Mellody K, Shuttleworth CA, Baldock C, Kielty CM. Marson A, et al. J Biol Chem. 2005 Feb 11;280(6):5013-21. doi: 10.1074/jbc.M409029200. Epub 2004 Nov 29. J Biol Chem. 2005. PMID: 15569675 Free article.

6

Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation.

Bax DV, Mahalingam Y, Cain S, Mellody K, Freeman L, Younger K, Shuttleworth CA, Humphries MJ, Couchman JR, Kielty CM. Bax DV, et al. J Cell Sci. 2007 Apr 15;120(Pt 8):1383-92. doi: 10.1242/jcs.003954. Epub 2007 Mar 20. J Cell Sci. 2007. PMID: 17374638 Free article.

7

Marfan syndrome-causing mutations in fibrillin-1 result in gross morphological alterations and highlight the structural importance of the second hybrid domain.

Mellody KT, Freeman LJ, Baldock C, Jowitt TA, Siegler V, Raynal BD, Cain SA, Wess TJ, Shuttleworth CA, Kielty CM. Mellody KT, et al. J Biol Chem. 2006 Oct 20;281(42):31854-62. doi: 10.1074/jbc.M602743200. Epub 2006 Aug 10. J Biol Chem. 2006. PMID: 16905551 Free article.

8

Fibulin-5 interacts with fibrillin-1 molecules and microfibrils.

Freeman LJ, Lomas A, Hodson N, Sherratt MJ, Mellody KT, Weiss AS, Shuttleworth A, Kielty CM. Freeman LJ, et al. Among authors: mellody kt. Biochem J. 2005 May 15;388(Pt 1):1-5. doi: 10.1042/BJ20050368. Biochem J. 2005. PMID: 15790312 Free PMC article.

9

Fibulin-5 binds human smooth-muscle cells through alpha5beta1 and alpha4beta1 integrins, but does not support receptor activation.

Lomas AC, Mellody KT, Freeman LJ, Bax DV, Shuttleworth CA, Kielty CM. Lomas AC, et al. Among authors: mellody kt. Biochem J. 2007 Aug 1;405(3):417-28. doi: 10.1042/BJ20070400. Biochem J. 2007. PMID: 17472576 Free PMC article.

10

Fibrillin-1 microfibril deposition is dependent on fibronectin assembly.

Kinsey R, Williamson MR, Chaudhry S, Mellody KT, McGovern A, Takahashi S, Shuttleworth CA, Kielty CM. Kinsey R, et al. Among authors: mellody kt. J Cell Sci. 2008 Aug 15;121(Pt 16):2696-704. doi: 10.1242/jcs.029819. Epub 2008 Jul 24. J Cell Sci. 2008. PMID: 18653538

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