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Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice.
Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, Akhtar M, Thompson JE, Melov S, Mocellin NJ, Kujoth GC, Prolla TA, Tarnopolsky MA. Safdar A, et al. Among authors: melov s. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4135-40. doi: 10.1073/pnas.1019581108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368114 Free PMC article.
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
Melov S, Adlard PA, Morten K, Johnson F, Golden TR, Hinerfeld D, Schilling B, Mavros C, Masters CL, Volitakis I, Li QX, Laughton K, Hubbard A, Cherny RA, Gibson B, Bush AI. Melov S, et al. PLoS One. 2007 Jun 20;2(6):e536. doi: 10.1371/journal.pone.0000536. PLoS One. 2007. PMID: 17579710 Free PMC article.
Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
Brand MD, Goncalves RL, Orr AL, Vargas L, Gerencser AA, Borch Jensen M, Wang YT, Melov S, Turk CN, Matzen JT, Dardov VJ, Petrassi HM, Meeusen SL, Perevoshchikova IV, Jasper H, Brookes PS, Ainscow EK. Brand MD, et al. Among authors: melov s. Cell Metab. 2016 Oct 11;24(4):582-592. doi: 10.1016/j.cmet.2016.08.012. Epub 2016 Sep 22. Cell Metab. 2016. PMID: 27667666 Free PMC article.
SOD2 in mitochondrial dysfunction and neurodegeneration.
Flynn JM, Melov S. Flynn JM, et al. Among authors: melov s. Free Radic Biol Med. 2013 Sep;62:4-12. doi: 10.1016/j.freeradbiomed.2013.05.027. Epub 2013 May 29. Free Radic Biol Med. 2013. PMID: 23727323 Free PMC article. Review.
Mitochondrial reactive oxygen species in mice lacking superoxide dismutase 2: attenuation via antioxidant treatment.
Morten KJ, Ackrell BA, Melov S. Morten KJ, et al. Among authors: melov s. J Biol Chem. 2006 Feb 10;281(6):3354-9. doi: 10.1074/jbc.M509261200. Epub 2005 Dec 2. J Biol Chem. 2006. PMID: 16326710
S., Zastawny, T. H., Dizdaroglu, M., Goodman, S. I., Huang, T. T., Miziorko, H., Epstein, C. J., and Wallace, D. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 846-851 and Li, Y., Huang, T. T., Carlson, E. J., Melov, S., Ursell, P. ...
S., Zastawny, T. H., Dizdaroglu, M., Goodman, S. I., Huang, T. T., Miziorko, H., Epstein, C. J., and Wallace, D. C. (1999) Pro
Expression patterns of cardiac aging in Drosophila.
Cannon L, Zambon AC, Cammarato A, Zhang Z, Vogler G, Munoz M, Taylor E, Cartry J, Bernstein SI, Melov S, Bodmer R. Cannon L, et al. Among authors: melov s. Aging Cell. 2017 Feb;16(1):82-92. doi: 10.1111/acel.12559. Aging Cell. 2017. PMID: 28090760 Free PMC article.
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