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HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
Zecher BF, Ellinghaus D, Schloer S, Niehrs A, Padoan B, Baumdick ME, Yuki Y, Martin MP, Glow D, Schröder-Schwarz J, Niersch J, Brias S, Müller LM, Habermann R, Kretschmer P, Früh T, Dänekas J, Wehmeyer MH, Poch T, Sebode M; International PSC Study Group (IPSCSG); Ellinghaus E, Degenhardt F, Körner C, Hoelzemer A, Fehse B, Oldhafer KJ, Schumacher U, Sauter G, Carrington M, Franke A, Bunders MJ, Schramm C, Altfeld M. Zecher BF, et al. Gut. 2024 Jan 5;73(2):325-337. doi: 10.1136/gutjnl-2023-329524. Gut. 2024. PMID: 37788895 Free PMC article.
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis.
Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F. Vesterhus M, et al. Among authors: melum e. J Hepatol. 2017 Jun;66(6):1214-1222. doi: 10.1016/j.jhep.2017.01.019. Epub 2017 Feb 2. J Hepatol. 2017. PMID: 28161472
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction.
Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A. Louwe MC, et al. Among authors: melum e. JACC Basic Transl Sci. 2020 Dec 9;5(12):1210-1224. doi: 10.1016/j.jacbts.2020.09.013. eCollection 2020 Dec. JACC Basic Transl Sci. 2020. PMID: 33426377 Free PMC article.
Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.
Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH; IBSEN Study Group; Stokkers PC, Vermeire S, Mathew CG, Lie BA, Beuers U, Manns MP, Schreiber S, Schrumpf E, Häussinger D, Franke A, Karlsen TH. Hov JR, et al. Among authors: melum e. PLoS One. 2010 Aug 25;5(8):e12403. doi: 10.1371/journal.pone.0012403. PLoS One. 2010. PMID: 20811628 Free PMC article.
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree.
Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E. Berntsen NL, et al. Among authors: melum e. Am J Physiol Gastrointest Liver Physiol. 2018 Mar 1;314(3):G349-G359. doi: 10.1152/ajpgi.00124.2017. Epub 2017 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29212771 Free article.
Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population.
Næss S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJ, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH. Næss S, et al. Among authors: melum e. PLoS One. 2014 Dec 18;9(12):e114486. doi: 10.1371/journal.pone.0114486. eCollection 2014. PLoS One. 2014. PMID: 25521205 Free PMC article.
The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation.
Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E. Schrumpf E, et al. Among authors: melum e. J Hepatol. 2017 Feb;66(2):382-389. doi: 10.1016/j.jhep.2016.09.020. Epub 2016 Oct 5. J Hepatol. 2017. PMID: 27720803 Free PMC article.
94 results