Menéndez N - Search Results

1

The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives.

Lombó F, Menéndez N, Salas JA, Méndez C. Lombó F, et al. Among authors: menendez n. Appl Microbiol Biotechnol. 2006 Nov;73(1):1-14. doi: 10.1007/s00253-006-0511-6. Epub 2006 Sep 30. Appl Microbiol Biotechnol. 2006. PMID: 17013601 Review.

2

A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis.

Núñez LE, Nybo SE, González-Sabín J, Pérez M, Menéndez N, Braña AF, Shaaban KA, He M, Morís F, Salas JA, Rohr J, Méndez C. Núñez LE, et al. Among authors: menendez n. J Med Chem. 2012 Jun 28;55(12):5813-25. doi: 10.1021/jm300234t. Epub 2012 Jun 7. J Med Chem. 2012. PMID: 22578073 Free PMC article.

3

The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin.

García B, González-Sabín J, Menéndez N, Braña AF, Núñez LE, Morís F, Salas JA, Méndez C. García B, et al. Among authors: menendez n. Microb Biotechnol. 2011 Mar;4(2):226-38. doi: 10.1111/j.1751-7915.2010.00229.x. Epub 2010 Nov 18. Microb Biotechnol. 2011. PMID: 21342468 Free PMC article.

4

Involvement of a chromomycin ABC transporter system in secretion of a deacetylated precursor during chromomycin biosynthesis.

Menéndez N, Braña AF, Salas JA, Méndez C. Menéndez N, et al. Microbiology (Reading). 2007 Sep;153(Pt 9):3061-3070. doi: 10.1099/mic.0.2007/007922-0. Microbiology (Reading). 2007. PMID: 17768249

5

Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity.

Menéndez N, Nur-e-Alam M, Fischer C, Braña AF, Salas JA, Rohr J, Méndez C. Menéndez N, et al. Appl Environ Microbiol. 2006 Jan;72(1):167-77. doi: 10.1128/AEM.72.1.167-177.2006. Appl Environ Microbiol. 2006. PMID: 16391039 Free PMC article.

6

Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs.

Menéndez N, Nur-e-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Menéndez N, et al. Chem Biol. 2004 Jan;11(1):21-32. doi: 10.1016/j.chembiol.2003.12.011. Chem Biol. 2004. PMID: 15112992

7

Tailoring modification of deoxysugars during biosynthesis of the antitumour drug chromomycin A by Streptomyces griseus ssp. griseus.

Menéndez N, Nur-E-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Menéndez N, et al. Mol Microbiol. 2004 Aug;53(3):903-15. doi: 10.1111/j.1365-2958.2004.04166.x. Mol Microbiol. 2004. PMID: 15255901

8

Increased heterologous production of the antitumoral polyketide mithramycin A by engineered Streptomyces lividans TK24 strains.

Novakova R, Núñez LE, Homerova D, Knirschova R, Feckova L, Rezuchova B, Sevcikova B, Menéndez N, Morís F, Cortés J, Kormanec J. Novakova R, et al. Among authors: menendez n. Appl Microbiol Biotechnol. 2018 Jan;102(2):857-869. doi: 10.1007/s00253-017-8642-5. Epub 2017 Dec 1. Appl Microbiol Biotechnol. 2018. PMID: 29196786

9

Correction to: Increased heterologous production of the antitumoral polyketide mithramycin a by engineered Streptomyces lividans TK24 strains.

Novakova R, Núñez LE, Homerova D, Knirschova R, Feckova L, Rezuchova B, Sevcikova B, Menéndez N, Morís F, Cortés J, Kormanec J. Novakova R, et al. Among authors: menendez n. Appl Microbiol Biotechnol. 2018 Jan;102(2):871. doi: 10.1007/s00253-017-8710-x. Appl Microbiol Biotechnol. 2018. PMID: 29279959

10

Lipase-catalyzed preparation of chromomycin A₃ analogues and biological evaluation for anticancer activity.

González-Sabín J, Núñez LE, Menéndez N, Braña AF, Méndez C, Salas JA, Gotor V, Morís F. González-Sabín J, et al. Among authors: menendez n. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4310-3. doi: 10.1016/j.bmcl.2012.05.015. Epub 2012 May 11. Bioorg Med Chem Lett. 2012. PMID: 22647722

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