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Page 1
Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.
Loan Nguyen TM, Guilloux JP, Defaix C, Mendez-David I, Etting I, Alvarez JC, McGowan JC, Highland JN, Zanos P, Lovett J, Moaddel R, Corruble E, David DJ, Gould TD, Denny CA, Gardier AM. Loan Nguyen TM, et al. Among authors: mendez david i. Neuropharmacology. 2024 Nov 1;258:110065. doi: 10.1016/j.neuropharm.2024.110065. Epub 2024 Jul 14. Neuropharmacology. 2024. PMID: 39004413 Free PMC article.
Prophylactic efficacy of 5-HT4R agonists against stress.
Chen BK, Mendez-David I, Luna VM, Faye C, Gardier AM, David DJ, Denny CA. Chen BK, et al. Among authors: mendez david i. Neuropsychopharmacology. 2020 Feb;45(3):542-552. doi: 10.1038/s41386-019-0540-3. Epub 2019 Oct 10. Neuropsychopharmacology. 2020. PMID: 31600767 Free PMC article.
A Tale of Two Receptors: Simultaneous Targeting of NMDA Receptors and 5-HT4 Receptors Exerts Additional Effects Against Stress.
Chen BK, Jin M, Turi GF, Luna VM, Shah A, Moniz T, Shannon ME, Pauers M, Williams BL, Pham V, Hunsberger HC, Gardier AM, Mendez-David I, David DJ, Denny CA. Chen BK, et al. Among authors: mendez david i. Biol Psychiatry. 2026 Jul 1;100(1):44-63. doi: 10.1016/j.biopsych.2025.09.011. Epub 2025 Oct 1. Biol Psychiatry. 2026. PMID: 41043535 Free article.
Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine.
Chen BK, Luna VM, LaGamma CT, Xu X, Deng SX, Suckow RF, Cooper TB, Shah A, Brachman RA, Mendez-David I, David DJ, Gardier AM, Landry DW, Denny CA. Chen BK, et al. Among authors: mendez david i. Neuropsychopharmacology. 2020 Aug;45(9):1545-1556. doi: 10.1038/s41386-020-0714-z. Epub 2020 May 17. Neuropsychopharmacology. 2020. PMID: 32417852 Free PMC article.
34 results