Mendrala AL - Search Results

1

In vitro metabolism of methylene chloride in human and animal tissues: use in physiologically based pharmacokinetic models.

Reitz RH, Mendrala AL, Guengerich FP. Reitz RH, et al. Among authors: mendrala al. Toxicol Appl Pharmacol. 1989 Feb;97(2):230-46. doi: 10.1016/0041-008x(89)90328-1. Toxicol Appl Pharmacol. 1989. PMID: 2922756

2

Strategies to assess systemic exposure of chemicals in subchronic/chronic diet and drinking water studies.

Saghir SA, Mendrala AL, Bartels MJ, Day SJ, Hansen SC, Sushynski JM, Bus JS. Saghir SA, et al. Among authors: mendrala al. Toxicol Appl Pharmacol. 2006 Mar 15;211(3):245-60. doi: 10.1016/j.taap.2005.06.010. Epub 2005 Jul 22. Toxicol Appl Pharmacol. 2006. PMID: 16040073

3

A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans.

Timchalk C, Nolan RJ, Mendrala AL, Dittenber DA, Brzak KA, Mattsson JL. Timchalk C, et al. Among authors: mendrala al. Toxicol Sci. 2002 Mar;66(1):34-53. doi: 10.1093/toxsci/66.1.34. Toxicol Sci. 2002. PMID: 11861971 Clinical Trial.

4

Mechanistic aspects of the metabolism of 1,3-dichloropropene in rats and mice.

Bartels MJ, Brzak KA, Mendrala AL, Stott WT. Bartels MJ, et al. Among authors: mendrala al. Chem Res Toxicol. 2000 Nov;13(11):1096-102. doi: 10.1021/tx000124p. Chem Res Toxicol. 2000. PMID: 11087431

5

In vivo and in vitro studies of perchloroethylene metabolism for physiologically based pharmacokinetic modeling in rats, mice, and humans.

Reitz RH, Gargas ML, Mendrala AL, Schumann AM. Reitz RH, et al. Among authors: mendrala al. Toxicol Appl Pharmacol. 1996 Feb;136(2):289-306. doi: 10.1006/taap.1996.0036. Toxicol Appl Pharmacol. 1996. PMID: 8619237

6

In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human.

Mendrala AL, Langvardt PW, Nitschke KD, Quast JF, Nolan RJ. Mendrala AL, et al. Arch Toxicol. 1993;67(1):18-27. doi: 10.1007/BF02072030. Arch Toxicol. 1993. PMID: 8452475

7

Incorporation of in vitro enzyme data into the physiologically-based pharmacokinetic (PB-PK) model for methylene chloride: implications for risk assessment.

Reitz RH, Mendrala AL, Park CN, Andersen ME, Guengerich FP. Reitz RH, et al. Among authors: mendrala al. Toxicol Lett. 1988 Oct;43(1-3):97-116. doi: 10.1016/0378-4274(88)90023-9. Toxicol Lett. 1988. PMID: 3176073

8

Estimating the risk of liver cancer associated with human exposures to chloroform using physiologically based pharmacokinetic modeling.

Reitz RH, Mendrala AL, Corley RA, Quast JF, Gargas ML, Andersen ME, Staats DA, Conolly RB. Reitz RH, et al. Among authors: mendrala al. Toxicol Appl Pharmacol. 1990 Sep 15;105(3):443-59. doi: 10.1016/0041-008x(90)90148-n. Toxicol Appl Pharmacol. 1990. PMID: 2237918

9

Development of a physiologically based pharmacokinetic model for chloroform.

Corley RA, Mendrala AL, Smith FA, Staats DA, Gargas ML, Conolly RB, Andersen ME, Reitz RH. Corley RA, et al. Among authors: mendrala al. Toxicol Appl Pharmacol. 1990 May;103(3):512-27. doi: 10.1016/0041-008x(90)90324-n. Toxicol Appl Pharmacol. 1990. PMID: 2339423

10

Rapid uptake, metabolism, and elimination of inhaled sulfuryl fluoride fumigant by rats.

Mendrala AL, Markham DA, Eisenbrandt DL. Mendrala AL, et al. Toxicol Sci. 2005 Aug;86(2):239-47. doi: 10.1093/toxsci/kfi196. Epub 2005 May 11. Toxicol Sci. 2005. PMID: 15888664

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