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Vitamin D as an immune modulator in multiple sclerosis, a review.
Smolders J, Damoiseaux J, Menheere P, Hupperts R. Smolders J, et al. Among authors: menheere p. J Neuroimmunol. 2008 Feb;194(1-2):7-17. doi: 10.1016/j.jneuroim.2007.11.014. Epub 2008 Jan 4. J Neuroimmunol. 2008. PMID: 18177949 Review.
Periventricular white matter lucencies relate to low vitamin B12 levels in patients with small vessel stroke.
Pieters B, Staals J, Knottnerus I, Rouhl R, Menheere P, Kessels A, Lodder J. Pieters B, et al. Among authors: menheere p. Stroke. 2009 May;40(5):1623-6. doi: 10.1161/STROKEAHA.108.523431. Epub 2009 Mar 12. Stroke. 2009. PMID: 19286604
Circulating vitamin D binding protein levels are not associated with relapses or with vitamin D status in multiple sclerosis.
Smolders J, Peelen E, Thewissen M, Menheere P, Damoiseaux J, Hupperts R. Smolders J, et al. Among authors: menheere p. Mult Scler. 2014 Apr;20(4):433-7. doi: 10.1177/1352458513500552. Epub 2013 Aug 19. Mult Scler. 2014. PMID: 23959712
Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse.
Peelen E, Damoiseaux J, Smolders J, Knippenberg S, Menheere P, Tervaert JW, Hupperts R, Thewissen M. Peelen E, et al. Among authors: menheere p. J Neuroimmunol. 2011 Dec 15;240-241:97-103. doi: 10.1016/j.jneuroim.2011.09.013. Epub 2011 Oct 26. J Neuroimmunol. 2011. PMID: 22035960
Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission.
Knippenberg S, Peelen E, Smolders J, Thewissen M, Menheere P, Cohen Tervaert JW, Hupperts R, Damoiseaux J. Knippenberg S, et al. Among authors: menheere p. J Neuroimmunol. 2011 Oct 28;239(1-2):80-6. doi: 10.1016/j.jneuroim.2011.08.019. Epub 2011 Sep 21. J Neuroimmunol. 2011. PMID: 21940055
Vitamin D-related gene expression profiles in immune cells of patients with relapsing remitting multiple sclerosis.
Smolders J, Thewissen M, Theunissen R, Peelen E, Knippenberg S, Menheere P, Cohen Tervaert JW, Hupperts R, Damoiseaux J. Smolders J, et al. Among authors: menheere p. J Neuroimmunol. 2011 Jun;235(1-2):91-7. doi: 10.1016/j.jneuroim.2011.03.012. Epub 2011 Apr 20. J Neuroimmunol. 2011. PMID: 21507492
Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis.
Smolders J, Peelen E, Thewissen M, Cohen Tervaert JW, Menheere P, Hupperts R, Damoiseaux J. Smolders J, et al. Among authors: menheere p. PLoS One. 2010 Dec 13;5(12):e15235. doi: 10.1371/journal.pone.0015235. PLoS One. 2010. PMID: 21179201 Free PMC article.
Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis.
Smolders J, Menheere P, Thewissen M, Peelen E, Tervaert JW, Hupperts R, Damoiseaux J. Smolders J, et al. Among authors: menheere p. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):243-6. doi: 10.1016/j.jsbmb.2010.03.001. Epub 2010 Mar 6. J Steroid Biochem Mol Biol. 2010. PMID: 20211254
Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis.
Smolders J, Damoiseaux J, Menheere P, Tervaert JW, Hupperts R. Smolders J, et al. Among authors: menheere p. Ann N Y Acad Sci. 2009 Sep;1173:515-20. doi: 10.1111/j.1749-6632.2009.04656.x. Ann N Y Acad Sci. 2009. PMID: 19758194
Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis.
Smolders J, Thewissen M, Peelen E, Menheere P, Tervaert JW, Damoiseaux J, Hupperts R. Smolders J, et al. Among authors: menheere p. PLoS One. 2009 Aug 13;4(8):e6635. doi: 10.1371/journal.pone.0006635. PLoS One. 2009. PMID: 19675671 Free PMC article.
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