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Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction.
Mani SK, Kern CB, Kimbrough D, Addy B, Kasiganesan H, Rivers WT, Patel RK, Chou JC, Spinale FG, Mukherjee R, Menick DR. Mani SK, et al. Among authors: menick dr. Am J Physiol Heart Circ Physiol. 2015 Jun 1;308(11):H1391-401. doi: 10.1152/ajpheart.00390.2014. Epub 2015 Mar 20. Am J Physiol Heart Circ Physiol. 2015. PMID: 25795711 Free PMC article.
Mutations in DCHS1 cause mitral valve prolapse.
Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA. Durst R, et al. Among authors: menick dr. Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10. Nature. 2015. PMID: 26258302 Free PMC article.
Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1.
Xu L, Kappler CS, Mani SK, Shepherd NR, Renaud L, Snider P, Conway SJ, Menick DR. Xu L, et al. Among authors: menick dr. J Biol Chem. 2009 Oct 2;284(40):27265-72. doi: 10.1074/jbc.M109.022855. Epub 2009 Aug 6. J Biol Chem. 2009. PMID: 19661061 Free PMC article.
89 results