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Blockade of cannabinoid type 1 receptors augments the antiparkinsonian action of levodopa without affecting dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeys.
Cao X, Liang L, Hadcock JR, Iredale PA, Griffith DA, Menniti FS, Factor S, Greenamyre JT, Papa SM. Cao X, et al. Among authors: menniti fs. J Pharmacol Exp Ther. 2007 Oct;323(1):318-26. doi: 10.1124/jpet.107.125666. Epub 2007 Jul 13. J Pharmacol Exp Ther. 2007. PMID: 17630359
An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder.
Preskorn SH, Baker B, Kolluri S, Menniti FS, Krams M, Landen JW. Preskorn SH, et al. Among authors: menniti fs. J Clin Psychopharmacol. 2008 Dec;28(6):631-7. doi: 10.1097/JCP.0b013e31818a6cea. J Clin Psychopharmacol. 2008. PMID: 19011431 Clinical Trial.
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