Menolfi Demis [Full author name] - Search Results

Year	Number of Results
2012	1
2014	1
2015	4
2016	1
2018	1
2019	1
2020	2
2021	6
2022	1
2023	4
2024	2
2025	1
2026	1

1

Visualization and quantification of rDNA instabilities in mammalian cells and mouse models.

Zhu X, Jiang W, Wu W, Lee BJ, Menolfi D, Tubbs A, Cupo OM, Malkovskiy E, Nester M, Wang XS, Sims PA, Lin CV, Symington L, Nussenzweig A, McStay B, Zha S. Zhu X, et al. Among authors: menolfi d. Nucleic Acids Res. 2026 Jan 14;54(2):gkaf1523. doi: 10.1093/nar/gkaf1523. Nucleic Acids Res. 2026. PMID: 41533570 Free PMC article.

2

Exploring patterns in molecular biology.

Menolfi D. Menolfi D. Mol Cell. 2025 Jan 16;85(2):191-192. doi: 10.1016/j.molcel.2024.12.020. Epub 2025 Jan 16. Mol Cell. 2025. PMID: 39824160 Free article. No abstract available.

3

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Huang X, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Lin X, et al. Among authors: menolfi d. Mol Cell. 2024 Oct 17;84(20):3916-3931.e7. doi: 10.1016/j.molcel.2024.09.020. Epub 2024 Oct 8. Mol Cell. 2024. PMID: 39383878 Free PMC article.

4

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Lin X, et al. Among authors: menolfi d. bioRxiv [Preprint]. 2024 Mar 14:2024.03.12.584665. doi: 10.1101/2024.03.12.584665. bioRxiv. 2024. Update in: Mol Cell. 2024 Oct 17;84(20):3916-3931.e7. doi: 10.1016/j.molcel.2024.09.020. PMID: 38559022 Free PMC article. Updated. Preprint.

5

Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements.

Li Z, Duan S, Hua X, Xu X, Li Y, Menolfi D, Zhou H, Lu C, Zha S, Goff SP, Zhang Z. Li Z, et al. Among authors: menolfi d. Nature. 2023 Nov;623(7987):643-651. doi: 10.1038/s41586-023-06711-3. Epub 2023 Nov 8. Nature. 2023. PMID: 37938774 Free PMC article.

6

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S. Menolfi D, et al. Nat Commun. 2023 Jun 19;14(1):3618. doi: 10.1038/s41467-023-39332-5. Nat Commun. 2023. PMID: 37336885 Free PMC article.

7

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S. Menolfi D, et al. bioRxiv [Preprint]. 2023 May 27:2023.05.26.542515. doi: 10.1101/2023.05.26.542515. bioRxiv. 2023. Update in: Nat Commun. 2023 Jun 19;14(1):3618. doi: 10.1038/s41467-023-39332-5. PMID: 37292881 Free PMC article. Updated. Preprint.

8

70 years of the DNA double helix: An interview with Daniela Rhodes.

Menolfi D, Rhodes D. Menolfi D, et al. Mol Cell. 2023 Apr 20;83(8):1200-1203. doi: 10.1016/j.molcel.2023.03.028. Mol Cell. 2023. PMID: 37084710 Free article.

9

Targeting BRCA-mutated tumors in mitosis.

Menolfi D, Zha S. Menolfi D, et al. Nat Cancer. 2021 Dec;2(12):1296-1297. doi: 10.1038/s43018-021-00293-7. Nat Cancer. 2021. PMID: 35121918 No abstract available.

10

DNA-PKcs kinase activity orchestrates both end-processing and end-ligation.

Menolfi D, Zha S. Menolfi D, et al. Trends Cell Biol. 2022 Feb;32(2):91-93. doi: 10.1016/j.tcb.2021.12.002. Epub 2021 Dec 22. Trends Cell Biol. 2022. PMID: 34953661

11

DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.

Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, Zha S. Wang XS, et al. Among authors: menolfi d. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2105440118. doi: 10.1073/pnas.2105440118. Proc Natl Acad Sci U S A. 2021. PMID: 34521752 Free PMC article.

12

Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites.

Agashe S, Joseph CR, Reyes TAC, Menolfi D, Giannattasio M, Waizenegger A, Szakal B, Branzei D. Agashe S, et al. Among authors: menolfi d. Nat Commun. 2021 Apr 8;12(1):2111. doi: 10.1038/s41467-021-22217-w. Nat Commun. 2021. PMID: 33833229 Free PMC article.

13

FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis.

Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S. Milanovic M, et al. Among authors: menolfi d. J Immunol. 2021 Mar 15;206(6):1228-1239. doi: 10.4049/jimmunol.2000967. Epub 2021 Feb 3. J Immunol. 2021. PMID: 33536256 Free PMC article.

14

The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange.

Milanovic M, Sprinzen L, Menolfi D, Lee JH, Yamamoto K, Li Y, Lee BJ, Xu J, Estes VM, Wang D, Mckinnon PJ, Paull TT, Zha S. Milanovic M, et al. Among authors: menolfi d. Cancer Res. 2021 Jan 15;81(2):426-437. doi: 10.1158/0008-5472.CAN-20-2447. Epub 2020 Nov 25. Cancer Res. 2021. PMID: 33239428 Free PMC article.

15

ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion.

Menolfi D, Zha S. Menolfi D, et al. Cell Biosci. 2020 Jan 29;10:8. doi: 10.1186/s13578-020-0376-x. eCollection 2020. Cell Biosci. 2020. PMID: 32015826 Free PMC article. Review.

16

Using Cell Cycle-Restricted Alleles to Study the Chromatin Dynamics and Functions of the Structural Maintenance of Chromosomes (SMC) Complexes In Vivo.

Menolfi D, Branzei D. Menolfi D, et al. Methods Mol Biol. 2019;2004:3-16. doi: 10.1007/978-1-4939-9520-2_1. Methods Mol Biol. 2019. PMID: 31147905

17

Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.

Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S. Menolfi D, et al. Nat Commun. 2018 Dec 17;9(1):5351. doi: 10.1038/s41467-018-07798-3. Nat Commun. 2018. PMID: 30559436 Free PMC article.

18

Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.

Menolfi D, Delamarre A, Lengronne A, Pasero P, Branzei D. Menolfi D, et al. Mol Cell. 2015 Dec 17;60(6):835-46. doi: 10.1016/j.molcel.2015.10.023. Epub 2015 Nov 19. Mol Cell. 2015. PMID: 26698660 Free PMC article.

19

G2/M chromosome transactions essentially relying on Smc5/6.

Branzei D, Menolfi D. Branzei D, et al. Among authors: menolfi d. Cell Cycle. 2016;15(5):611-2. doi: 10.1080/15384101.2015.1131525. Epub 2015 Dec 22. Cell Cycle. 2016. PMID: 26694861 Free PMC article. No abstract available.

20

Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.

Urulangodi M, Sebesta M, Menolfi D, Szakal B, Sollier J, Sisakova A, Krejci L, Branzei D. Urulangodi M, et al. Among authors: menolfi d. Genes Dev. 2015 Oct 1;29(19):2067-80. doi: 10.1101/gad.265629.115. Genes Dev. 2015. PMID: 26443850 Free PMC article.

21

Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.

Hang LE, Peng J, Tan W, Szakal B, Menolfi D, Sheng Z, Lobachev K, Branzei D, Feng W, Zhao X. Hang LE, et al. Among authors: menolfi d. Mol Cell. 2015 Oct 15;60(2):268-79. doi: 10.1016/j.molcel.2015.08.023. Epub 2015 Oct 1. Mol Cell. 2015. PMID: 26439300 Free PMC article.

22

DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity.

Gonzalez-Huici V, Szakal B, Urulangodi M, Psakhye I, Castellucci F, Menolfi D, Rajakumara E, Fumasoni M, Bermejo R, Jentsch S, Branzei D. Gonzalez-Huici V, et al. Among authors: menolfi d. EMBO J. 2014 Feb 18;33(4):327-40. doi: 10.1002/embj.201387425. Epub 2014 Jan 28. EMBO J. 2014. PMID: 24473148 Free PMC article.

23

During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks.

Bustard DE, Menolfi D, Jeppsson K, Ball LG, Dewey SC, Shirahige K, Sjögren C, Branzei D, Cobb JA. Bustard DE, et al. Among authors: menolfi d. J Biol Chem. 2012 Mar 30;287(14):11374-83. doi: 10.1074/jbc.M111.336263. Epub 2012 Feb 2. J Biol Chem. 2012. PMID: 22303010 Free PMC article.

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