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Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Russo AJ, Vasudevan SO, Méndez-Huergo SP, Kumari P, Menoret A, Duduskar S, Wang C, Pérez Sáez JM, Fettis MM, Li C, Liu R, Wanchoo A, Chandiran K, Ruan J, Vanaja SK, Bauer M, Sponholz C, Hudalla GA, Vella AT, Zhou B, Deshmukh SD, Rabinovich GA, Rathinam VA. Russo AJ, et al. Among authors: menoret a. Nat Immunol. 2021 Feb;22(2):154-165. doi: 10.1038/s41590-020-00844-7. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398185 Free PMC article.
The oxazolidinone derivative locostatin induces cytokine appeasement.
Ménoret A, McAleer JP, Ngoi SM, Ray S, Eddy NA, Fenteany G, Lee SJ, Rossi RJ, Mukherji B, Allen DL, Chakraborty NG, Vella AT. Ménoret A, et al. J Immunol. 2009 Dec 1;183(11):7489-96. doi: 10.4049/jimmunol.0901414. Epub 2009 Nov 16. J Immunol. 2009. PMID: 19917702 Free PMC article.
77 results