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A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
Mente A, de Koning L, Shannon HS, Anand SS. Mente A, et al. Arch Intern Med. 2009 Apr 13;169(7):659-69. doi: 10.1001/archinternmed.2009.38. Arch Intern Med. 2009. PMID: 19364995 Review.
BACKGROUND: Although a wealth of literature links dietary factors and coronary heart disease (CHD), the strength of the evidence supporting valid associations has not been evaluated systematically in a single investigation. ...CONCLUSIONS: The evidence supports a
BACKGROUND: Although a wealth of literature links dietary factors and coronary heart disease (CHD), the strength of the evidence supp …
Relationship of the ApoE polymorphism to plasma lipid traits among South Asians, Chinese, and Europeans living in Canada.
Burman D, Mente A, Hegele RA, Islam S, Yusuf S, Anand SS. Burman D, et al. Atherosclerosis. 2009 Mar;203(1):192-200. doi: 10.1016/j.atherosclerosis.2008.06.007. Epub 2008 Jun 20. Atherosclerosis. 2009. PMID: 18656198
There was a strong, stepwise association between ApoE and each plasma lipid trait, except triglycerides. The E4 genotype was associated with higher low-density lipoprotein cholesterol (p for trend<0.001), ApoB (p<0.001), ApoB/ApoA ratio (p<0.001) and lipoprotein ( …
There was a strong, stepwise association between ApoE and each plasma lipid trait, except triglycerides. The E4 genotype was associat …
Urinary sodium and potassium excretion and risk of cardiovascular events.
O'Donnell MJ, Yusuf S, Mente A, Gao P, Mann JF, Teo K, McQueen M, Sleight P, Sharma AM, Dans A, Probstfield J, Schmieder RE. O'Donnell MJ, et al. JAMA. 2011 Nov 23;306(20):2229-38. doi: 10.1001/jama.2011.1729. JAMA. 2011. PMID: 22110105 Clinical Trial.
After a median follow-up of 56 months, the composite outcome occurred in 4729 (16.4%) participants, including 2057 CV deaths, 1412 with MI, 1282 with stroke, and 1213 with hospitalization for CHF. ...Higher estimated potassium excretion was associated with a reduced …
After a median follow-up of 56 months, the composite outcome occurred in 4729 (16.4%) participants, including 2057 CV deaths, 1412 wi …
Development, reproducibility and validity of the food frequency questionnaire in the Poland arm of the Prospective Urban and Rural Epidemiological (PURE) study.
Dehghan M, Ilow R, Zatonska K, Szuba A, Zhang X, Mente A, Regulska-Ilow B. Dehghan M, et al. J Hum Nutr Diet. 2012 Jun;25(3):225-32. doi: 10.1111/j.1365-277X.2012.01240.x. Epub 2012 Mar 6. J Hum Nutr Diet. 2012. PMID: 22390143
BACKGROUND: A food frequency questionnaire (FFQ) is the most commonly used method in large epidemiological studies. The validation of an FFQ is essential for specific populations because foods are culture-dependent. ...METHODS: Adult participants (n = 146) in the Polish ar …
BACKGROUND: A food frequency questionnaire (FFQ) is the most commonly used method in large epidemiological studies. The validation of …
Effects of higher- versus lower-protein diets on health outcomes: a systematic review and meta-analysis.
Santesso N, Akl EA, Bianchi M, Mente A, Mustafa R, Heels-Ansdell D, Schünemann HJ. Santesso N, et al. Eur J Clin Nutr. 2012 Jul;66(7):780-8. doi: 10.1038/ejcn.2012.37. Epub 2012 Apr 18. Eur J Clin Nutr. 2012. PMID: 22510792 Free PMC article. Review.
We conducted a rigorous systematic review of RCTs comparing higher- and lower-protein diets. METHODS: We searched several electronic databases up to July 2011 for studies focusing on patient-important outcomes (for example, cardiovascular disease) and secondary outcomes su …
We conducted a rigorous systematic review of RCTs comparing higher- and lower-protein diets. METHODS: We searched several electronic …
Relationship between healthy diet and risk of cardiovascular disease among patients on drug therapies for secondary prevention: a prospective cohort study of 31 546 high-risk individuals from 40 countries.
Dehghan M, Mente A, Teo KK, Gao P, Sleight P, Dagenais G, Avezum A, Probstfield JL, Dans T, Yusuf S; Ongoing Telmisartan Alone and in Combination With Ramipril Global End Point Trial (ONTARGET)/Telmisartan Randomized Assessment Study in ACEI Intolerant Subjects With Cardiovascular Disease (TRANSCEND) Trial Investigators. Dehghan M, et al. Circulation. 2012 Dec 4;126(23):2705-12. doi: 10.1161/CIRCULATIONAHA.112.103234. Circulation. 2012. PMID: 23212996 Clinical Trial.
This study assessed the association between diet quality and CVD events in a large population of subjects from 40 countries with CVD or diabetes mellitus with end-organ damage receiving proven medications. ...CONCLUSIONS: A higher-quality diet was associated with …
This study assessed the association between diet quality and CVD events in a large population of subjects from 40 countries with CVD …
Salt intake and cardiovascular disease: why are the data inconsistent?
O'Donnell MJ, Mente A, Smyth A, Yusuf S. O'Donnell MJ, et al. Eur Heart J. 2013 Apr;34(14):1034-40. doi: 10.1093/eurheartj/ehs409. Epub 2012 Dec 17. Eur Heart J. 2013. PMID: 23257945 Review.
Reducing salt intake has emerged as a leading target, with many guidelines recommending sodium intakes of 2.3 g/day or lower. ...In the largest of these studies, a J-shaped association between sodium intake and CV death and heart failure was found. Despite a
Reducing salt intake has emerged as a leading target, with many guidelines recommending sodium intakes of 2.3 g/day or lower. ...In t …
Extreme sodium reductions for the entire population: zealotry or evidence based?
Mente A, O'Donnell MJ, Yusuf S. Mente A, et al. Am J Hypertens. 2013 Oct;26(10):1187-90. doi: 10.1093/ajh/hpt148. Am J Hypertens. 2013. PMID: 24042546 No abstract available.
Impact of lifestyle factors on fracture risk in older patients with cardiovascular disease: a prospective cohort study of 26,335 individuals from 40 countries.
Khatib R, Yusuf S, Barzilay JI, Papaioannou A, Thabane L, Gao P, Joseph PG, Teo K, Mente A. Khatib R, et al. Age Ageing. 2014 Sep;43(5):629-35. doi: 10.1093/ageing/afu009. Epub 2014 Feb 18. Age Ageing. 2014. PMID: 24554790 Clinical Trial.
BACKGROUND: fractures are a major health concern among the elderly. People at risk for cardiovascular disease (CVD) are at an increased risk for fractures. ...CONCLUSIONS: a healthier lifestyle advocated to reduce the risk of CVD is associated with a signific …
BACKGROUND: fractures are a major health concern among the elderly. People at risk for cardiovascular disease (CVD) are at an increas …
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