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65 results

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Page 1
Editorial: Dysfunction and Repair of Neural Circuits for Motor Control.
Tosolini AP, Mentis GZ, Martin JH. Tosolini AP, et al. Among authors: mentis gz. Front Mol Neurosci. 2021 Mar 22;14:669824. doi: 10.3389/fnmol.2021.669824. eCollection 2021. Front Mol Neurosci. 2021. PMID: 33828459 Free PMC article. No abstract available.
SMN controls neuromuscular junction integrity through U7 snRNP.
Tisdale S, Van Alstyne M, Simon CM, Mentis GZ, Pellizzoni L. Tisdale S, et al. Among authors: mentis gz. Cell Rep. 2022 Sep 20;40(12):111393. doi: 10.1016/j.celrep.2022.111393. Cell Rep. 2022. PMID: 36130491 Free PMC article.
Synaptic imbalance and increased inhibition impair motor function in SMA.
Fletcher EV, Chalif JI, Rotterman TM, Pagiazitis JG, Alstyne MV, Sivakumar N, Rabinowitz JE, Pellizzoni L, Alvarez FJ, Mentis GZ. Fletcher EV, et al. Among authors: mentis gz. bioRxiv [Preprint]. 2024 Sep 1:2024.08.30.610545. doi: 10.1101/2024.08.30.610545. bioRxiv. 2024. PMID: 39257773 Free PMC article. Preprint.
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA.
Kong L, Valdivia DO, Simon CM, Hassinan CW, Delestrée N, Ramos DM, Park JH, Pilato CM, Xu X, Crowder M, Grzyb CC, King ZA, Petrillo M, Swoboda KJ, Davis C, Lutz CM, Stephan AH, Zhao X, Weetall M, Naryshkin NA, Crawford TO, Mentis GZ, Sumner CJ. Kong L, et al. Among authors: mentis gz. Sci Transl Med. 2021 Jan 27;13(578):eabb6871. doi: 10.1126/scitranslmed.abb6871. Sci Transl Med. 2021. PMID: 33504650 Free PMC article.
First-in-human study of epidural spinal cord stimulation in individuals with spinal muscular atrophy.
Prat-Ortega G, Ensel S, Donadio S, Borda L, Boos A, Yadav P, Verma N, Ho J, Carranza E, Frazier-Kim S, Fields DP, Fisher LE, Weber DJ, Balzer J, Duong T, Weinstein SD, Eliasson MJL, Montes J, Chen KS, Clemens PR, Gerszten P, Mentis GZ, Pirondini E, Friedlander RM, Capogrosso M. Prat-Ortega G, et al. Among authors: mentis gz. Nat Med. 2025 Apr;31(4):1246-1256. doi: 10.1038/s41591-024-03484-8. Epub 2025 Feb 5. Nat Med. 2025. PMID: 39910271 Clinical Trial.
Proprioceptive synaptic dysfunction is a key feature in mice and humans with spinal muscular atrophy.
Simon CM, Delestrée N, Montes J, Sowoidnich L, Gerstner F, Carranza E, Buettner JM, Pagiazitis JG, Prat-Ortega G, Ensel S, Donadio S, Dreilich V, Carlini MJ, Garcia JL, Kratimenos P, Chung WK, Sumner CJ, Weimer LH, Pirondini E, Capogrosso M, Pellizzoni L, De Vivo DC, Mentis GZ. Simon CM, et al. Among authors: mentis gz. Brain. 2025 Feb 21:awaf074. doi: 10.1093/brain/awaf074. Online ahead of print. Brain. 2025. PMID: 39982868
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