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Adenosine receptors and cancer.
Gessi S, Merighi S, Sacchetto V, Simioni C, Borea PA. Gessi S, et al. Among authors: merighi s. Biochim Biophys Acta. 2011 May;1808(5):1400-12. doi: 10.1016/j.bbamem.2010.09.020. Epub 2010 Oct 1. Biochim Biophys Acta. 2011. PMID: 20888788 Review.
Interestingly, the safety of such compounds has already been demonstrated in trials employing A(2A) antagonists in the treatment of Parkinson's disease. ...
Interestingly, the safety of such compounds has already been demonstrated in trials employing A(2A) antagonists in the treatment of Parkinso …
Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships.
Varani K, Calo G, Rizzi A, Merighi S, Toth G, Guerrini R, Salvadori S, Borea PA, Regoli D. Varani K, et al. Among authors: merighi s. Br J Pharmacol. 1998 Dec;125(7):1485-90. doi: 10.1038/sj.bjp.0702226. Br J Pharmacol. 1998. PMID: 9884077 Free PMC article.
Caffeine alters A2A adenosine receptors and their function in human platelets.
Varani K, Portaluppi F, Merighi S, Ongini E, Belardinelli L, Borea PA. Varani K, et al. Among authors: merighi s. Circulation. 1999 May 18;99(19):2499-502. doi: 10.1161/01.cir.99.19.2499. Circulation. 1999. PMID: 10330379
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists.
Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, Klotz KN, Leung E, Varani K, Gessi S, Merighi S, Borea PA. Baraldi PG, et al. Among authors: merighi s. J Med Chem. 1999 Nov 4;42(22):4473-8. doi: 10.1021/jm991114s. J Med Chem. 1999. PMID: 10579811 No abstract available.
A(2A) adenosine receptors in human peripheral blood cells.
Gessi S, Varani K, Merighi S, Ongini E, Borea PA. Gessi S, et al. Among authors: merighi s. Br J Pharmacol. 2000 Jan;129(1):2-11. doi: 10.1038/sj.bjp.0703045. Br J Pharmacol. 2000. PMID: 10694196 Free PMC article. Review. No abstract available.
Synthesis and preliminary biological evaluation of [3H]-MRE 3008-F20: the first high affinity radioligand antagonist for the human A3 adenosine receptors.
Baraldi PG, Cacciari B, Romagnoli R, Varani K, Merighi S, Gessi S, Borea PA, Leung E, Hickey SL, Spalluto G. Baraldi PG, et al. Among authors: merighi s. Bioorg Med Chem Lett. 2000 Feb 7;10(3):209-11. doi: 10.1016/s0960-894x(99)00674-5. Bioorg Med Chem Lett. 2000. PMID: 10698437
A(3) adenosine receptor ligands: history and perspectives.
Baraldi PG, Cacciari B, Romagnoli R, Merighi S, Varani K, Borea PA, Spalluto G. Baraldi PG, et al. Among authors: merighi s. Med Res Rev. 2000 Mar;20(2):103-28. doi: 10.1002/(sici)1098-1128(200003)20:2<103::aid-med1>3.0.co;2-x. Med Res Rev. 2000. PMID: 10723024 Review.
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
Varani K, Merighi S, Gessi S, Klotz KN, Leung E, Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, Borea PA. Varani K, et al. Among authors: merighi s. Mol Pharmacol. 2000 May;57(5):968-75. Mol Pharmacol. 2000. PMID: 10779381
Dose and time effects of caffeine intake on human platelet adenosine A(2A) receptors : functional and biochemical aspects.
Varani K, Portaluppi F, Gessi S, Merighi S, Ongini E, Belardinelli L, Borea PA. Varani K, et al. Among authors: merighi s. Circulation. 2000 Jul 18;102(3):285-9. doi: 10.1161/01.cir.102.3.285. Circulation. 2000. PMID: 10899090
Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists: influence of the chain at the N(8) pyrazole nitrogen.
Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, Moro S, Klotz KN, Leung E, Varani K, Gessi S, Merighi S, Borea PA. Baraldi PG, et al. Among authors: merighi s. J Med Chem. 2000 Dec 14;43(25):4768-80. doi: 10.1021/jm001047y. J Med Chem. 2000. PMID: 11123985
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