Merkel O - Search Results

1

CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review.

Babačić H, Mehta A, Merkel O, Schoser B. Babačić H, et al. Among authors: merkel o. PLoS One. 2019 Feb 22;14(2):e0212198. doi: 10.1371/journal.pone.0212198. eCollection 2019. PLoS One. 2019. PMID: 30794581 Free PMC article.

2

Targeting KRAS Mutant Lung Cancer Cells with siRNA-Loaded Bovine Serum Albumin Nanoparticles.

Mehta A, Dalle Vedove E, Isert L, Merkel OM. Mehta A, et al. Pharm Res. 2019 Jul 9;36(9):133. doi: 10.1007/s11095-019-2665-9. Pharm Res. 2019. PMID: 31289919 Free PMC article.

3

Coming in and Finding Out: Blending Receptor-Targeted Delivery and Efficient Endosomal Escape in a Novel Bio-Responsive siRNA Delivery System for Gene Knockdown in Pulmonary T Cells.

Kandil R, Xie Y, Heermann R, Isert L, Jung K, Mehta A, Merkel OM. Kandil R, et al. Adv Ther (Weinh). 2019 Jul;2(7):1900047. doi: 10.1002/adtp.201900047. Epub 2019 Apr 26. Adv Ther (Weinh). 2019. PMID: 31372493 Free PMC article.

4

A Method for Targeted Nonviral siRNA Delivery in Cancer and Inflammatory Diseases.

Kandil R, Xie Y, Mehta A, Merkel O. Kandil R, et al. Among authors: merkel o. Methods Mol Biol. 2020;2059:155-166. doi: 10.1007/978-1-4939-9798-5_7. Methods Mol Biol. 2020. PMID: 31435920 Free PMC article.

5

Immunogenicity of Cas9 Protein.

Mehta A, Merkel OM. Mehta A, et al. J Pharm Sci. 2020 Jan;109(1):62-67. doi: 10.1016/j.xphs.2019.10.003. Epub 2019 Oct 4. J Pharm Sci. 2020. PMID: 31589876 Free PMC article.

6

siRNA Therapeutics against Respiratory Viral Infections-What Have We Learned for Potential COVID-19 Therapies?

Mehta A, Michler T, Merkel OM. Mehta A, et al. Adv Healthc Mater. 2021 Apr;10(7):e2001650. doi: 10.1002/adhm.202001650. Epub 2021 Jan 27. Adv Healthc Mater. 2021. PMID: 33506607 Free PMC article. Review.

7

Impact of crystalline and amorphous matrices on successful spray drying of siRNA polyplexes for inhalation of nano-in-microparticles.

Keil TW, Zimmermann C, Baldassi D, Adams F, Friess W, Mehta A, Merkel OM. Keil TW, et al. Adv Ther (Weinh). 2021 May 7;4(6):2100073. doi: 10.1002/adtp.202100073. eCollection 2021 Jun. Adv Ther (Weinh). 2021. PMID: 34337144 Free PMC article.

8

Targeted GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma.

Kandil R, Baldassi D, Böhlen S, Müller JT, Jürgens DC, Bargmann T, Dehmel S, Xie Y, Mehta A, Sewald K, Merkel OM. Kandil R, et al. J Control Release. 2023 Feb;354:305-315. doi: 10.1016/j.jconrel.2023.01.014. Epub 2023 Jan 13. J Control Release. 2023. PMID: 36634709 Free PMC article.

9

An In Vitro Approach to Model EMT in Breast Cancer.

Isert L, Mehta A, Loiudice G, Oliva A, Roidl A, Merkel OM. Isert L, et al. Int J Mol Sci. 2023 Apr 24;24(9):7757. doi: 10.3390/ijms24097757. Int J Mol Sci. 2023. PMID: 37175467 Free PMC article.

10

Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score.

Rubio K, Müller JM, Mehta A, Watermann I, Olchers T, Koch I, Wessels S, Schneider MA, Araujo-Ramos T, Singh I, Kugler C, Stoleriu MG, Kriegsmann M, Eichhorn M, Muley T, Merkel OM, Braun T, Ammerpohl O, Reck M, Tresch A, Barreto G. Rubio K, et al. Among authors: merkel om. Discov Oncol. 2023 Oct 3;14(1):181. doi: 10.1007/s12672-023-00799-9. Discov Oncol. 2023. PMID: 37787775 Free PMC article.

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