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39 results
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Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal.
Pereira L, Yi F, Merrill BJ. Pereira L, et al. Among authors: merrill bj. Mol Cell Biol. 2006 Oct;26(20):7479-91. doi: 10.1128/MCB.00368-06. Epub 2006 Aug 7. Mol Cell Biol. 2006. PMID: 16894029 Free PMC article.
Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Zhu X, Clarke R, Puppala AK, Chittori S, Merk A, Merrill BJ, Simonović M, Subramaniam S. Zhu X, et al. Among authors: merrill bj. Nat Struct Mol Biol. 2019 Aug;26(8):679-685. doi: 10.1038/s41594-019-0258-2. Epub 2019 Jul 8. Nat Struct Mol Biol. 2019. PMID: 31285607 Free PMC article.
Co-incident insertion enables high efficiency genome engineering in mouse embryonic stem cells.
Shy BR, MacDougall MS, Clarke R, Merrill BJ. Shy BR, et al. Among authors: merrill bj. Nucleic Acids Res. 2016 Sep 19;44(16):7997-8010. doi: 10.1093/nar/gkw685. Epub 2016 Aug 2. Nucleic Acids Res. 2016. PMID: 27484482 Free PMC article.
Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans.
Gaston-Massuet C, McCabe MJ, Scagliotti V, Young RM, Carreno G, Gregory LC, Jayakody SA, Pozzi S, Gualtieri A, Basu B, Koniordou M, Wu CI, Bancalari RE, Rahikkala E, Veijola R, Lopponen T, Graziola F, Turton J, Signore M, Mousavy Gharavy SN, Charolidi N, Sokol SY, Andoniadou CL, Wilson SW, Merrill BJ, Dattani MT, Martinez-Barbera JP. Gaston-Massuet C, et al. Among authors: merrill bj. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E548-57. doi: 10.1073/pnas.1503346113. Epub 2016 Jan 13. Proc Natl Acad Sci U S A. 2016. PMID: 26764381 Free PMC article.
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.
Nguyen H, Merrill BJ, Polak L, Nikolova M, Rendl M, Shaver TM, Pasolli HA, Fuchs E. Nguyen H, et al. Among authors: merrill bj. Nat Genet. 2009 Oct;41(10):1068-75. doi: 10.1038/ng.431. Epub 2009 Aug 30. Nat Genet. 2009. PMID: 19718027 Free PMC article.
Tcf3: a transcriptional regulator of axis induction in the early embryo.
Merrill BJ, Pasolli HA, Polak L, Rendl M, García-García MJ, Anderson KV, Fuchs E. Merrill BJ, et al. Development. 2004 Jan;131(2):263-74. doi: 10.1242/dev.00935. Epub 2003 Dec 10. Development. 2004. PMID: 14668413
Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation.
Atlasi Y, Noori R, Gaspar C, Franken P, Sacchetti A, Rafati H, Mahmoudi T, Decraene C, Calin GA, Merrill BJ, Fodde R. Atlasi Y, et al. Among authors: merrill bj. PLoS Genet. 2013 May;9(5):e1003424. doi: 10.1371/journal.pgen.1003424. Epub 2013 May 2. PLoS Genet. 2013. PMID: 23658527 Free PMC article.
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal.
Yi F, Pereira L, Hoffman JA, Shy BR, Yuen CM, Liu DR, Merrill BJ. Yi F, et al. Among authors: merrill bj. Nat Cell Biol. 2011 Jun 19;13(7):762-70. doi: 10.1038/ncb2283. Nat Cell Biol. 2011. PMID: 21685894 Free PMC article.
TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency.
Sierra RA, Hoverter NP, Ramirez RN, Vuong LM, Mortazavi A, Merrill BJ, Waterman ML, Donovan PJ. Sierra RA, et al. Among authors: merrill bj. Development. 2018 Feb 23;145(4):dev161075. doi: 10.1242/dev.161075. Development. 2018. PMID: 29361574 Free PMC article.
Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/β-catenin signaling.
Shy BR, Wu CI, Khramtsova GF, Zhang JY, Olopade OI, Goss KH, Merrill BJ. Shy BR, et al. Among authors: merrill bj. Cell Rep. 2013 Jul 11;4(1):1-9. doi: 10.1016/j.celrep.2013.06.001. Epub 2013 Jun 27. Cell Rep. 2013. PMID: 23810553 Free PMC article.
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