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Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. Mertens J, et al. Cell Stem Cell. 2015 Dec 3;17(6):705-718. doi: 10.1016/j.stem.2015.09.001. Epub 2015 Oct 8. Cell Stem Cell. 2015. PMID: 26456686 Free PMC article.
Alzheimer's disease: distinct stages in neurogenic decline?
Adamowicz DH, Mertens J, Gage FH. Adamowicz DH, et al. Among authors: mertens j. Biol Psychiatry. 2015 Apr 15;77(8):680-2. doi: 10.1016/j.biopsych.2015.02.021. Biol Psychiatry. 2015. PMID: 25835286 No abstract available.
Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro.
Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez RV, Kellogg M, Gorris M, Galet B, Palomares V, Brown J, Bang AG, Mertens J, Böhnke L, Boyer L, Simon S, Gage FH. Bardy C, et al. Among authors: mertens j. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2725-34. doi: 10.1073/pnas.1504393112. Epub 2015 Apr 13. Proc Natl Acad Sci U S A. 2015. PMID: 25870293 Free PMC article.
Generation of functional human serotonergic neurons from fibroblasts.
Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Vadodaria KC, et al. Among authors: mertens j. Mol Psychiatry. 2016 Jan;21(1):49-61. doi: 10.1038/mp.2015.161. Epub 2015 Oct 27. Mol Psychiatry. 2016. PMID: 26503761
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.
Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study; Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. Mertens J, et al. Nature. 2015 Nov 5;527(7576):95-9. doi: 10.1038/nature15526. Epub 2015 Oct 28. Nature. 2015. PMID: 26524527 Free PMC article.
The different moods of human serotonergic neurons.
Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Vadodaria KC, et al. Among authors: mertens j. Mol Psychiatry. 2016 Jan;21(1):3. doi: 10.1038/mp.2015.202. Mol Psychiatry. 2016. PMID: 26678308 No abstract available.
562 results