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Page 1
APOBEC-Induced Mutagenesis in Cancer.
Mertz TM, Collins CD, Dennis M, Coxon M, Roberts SA. Mertz TM, et al. Annu Rev Genet. 2022 Nov 30;56:229-252. doi: 10.1146/annurev-genet-072920-035840. Epub 2022 Aug 26. Annu Rev Genet. 2022. PMID: 36028227 Review.
Genetic inhibitors of APOBEC3B-induced mutagenesis.
Mertz TM, Rice-Reynolds E, Nguyen L, Wood A, Cordero C, Bray N, Harcy V, Vyas RK, Mitchell D, Lobachev K, Roberts SA. Mertz TM, et al. Genome Res. 2023 Sep;33(9):1568-1581. doi: 10.1101/gr.277430.122. Epub 2023 Aug 2. Genome Res. 2023. PMID: 37532520 Free PMC article.
An impaired ubiquitin-proteasome system increases APOBEC3A abundance.
Coxon M, Dennis MA, Dananberg A, Collins CD, Wilson HE, Meekma J, Savenkova MI, Ng D, Osbron CA, Mertz TM, Goodman AG, Duttke SH, Maciejowski J, Roberts SA. Coxon M, et al. Among authors: mertz tm. NAR Cancer. 2023 Dec 19;5(4):zcad058. doi: 10.1093/narcan/zcad058. eCollection 2023 Dec. NAR Cancer. 2023. PMID: 38155930 Free PMC article.
Genetic modifiers of APOBEC-induced mutagenesis.
Mertz TM, Rice-Reynolds E, Nguyen L, Wood A, Bray N, Mitchell D, Lobachev K, Roberts SA. Mertz TM, et al. bioRxiv [Preprint]. 2023 Apr 6:2023.04.05.535598. doi: 10.1101/2023.04.05.535598. bioRxiv. 2023. PMID: 37066362 Free PMC article. Preprint.
APOBEC3A is a prominent cytidine deaminase in breast cancer.
Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA. Cortez LM, et al. Among authors: mertz tm. PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31841499 Free PMC article.
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.
Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung P, Das SR, Paeschke K, Roberts SA, VanDemark AP, Bernstein KA. Rosenbaum JC, et al. Among authors: mertz tm. Nat Commun. 2019 Aug 5;10(1):3515. doi: 10.1038/s41467-019-11374-8. Nat Commun. 2019. PMID: 31383866 Free PMC article.
17 results