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Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
Ando M, Saito Y, Xu G, Bui NQ, Medetgul-Ernar K, Pu M, Fisch K, Ren S, Sakai A, Fukusumi T, Liu C, Haft S, Pang J, Mark A, Gaykalova DA, Guo T, Favorov AV, Yegnasubramanian S, Fertig EJ, Ha P, Tamayo P, Yamasoba T, Ideker T, Messer K, Califano JA. Ando M, et al. Among authors: Messer K. Nat Commun. 2019 May 16;10(1):2188. doi: 10.1038/s41467-019-09937-w. Nat Commun. 2019. PMID: 31097695 Free PMC article.
Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms.
Jung B, Gomez J, Chau E, Cabral J, Lee JK, Anselm A, Slowik P, Ream-Robinson D, Messer K, Sporn J, Shin SK, Boland CR, Goel A, Carethers JM. Jung B, et al. Among authors: Messer K. PLoS One. 2009 Dec 14;4(12):e8308. doi: 10.1371/journal.pone.0008308. PLoS One. 2009. PMID: 20011542 Free PMC article.
ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice.
Widhopf GF 2nd, Cui B, Ghia EM, Chen L, Messer K, Shen Z, Briggs SP, Croce CM, Kipps TJ. Widhopf GF 2nd, et al. Among authors: Messer K. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):793-8. doi: 10.1073/pnas.1308374111. Epub 2013 Dec 30. Proc Natl Acad Sci U S A. 2014. PMID: 24379361 Free PMC article.
Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell development.
Smith EN, Ghia EM, DeBoever CM, Rassenti LZ, Jepsen K, Yoon KA, Matsui H, Rozenzhak S, Alakus H, Shepard PJ, Dai Y, Khosroheidari M, Bina M, Gunderson KL, Messer K, Muthuswamy L, Hudson TJ, Harismendy O, Barrett CL, Jamieson CH, Carson DA, Kipps TJ, Frazer KA. Smith EN, et al. Among authors: Messer K. Blood Cancer J. 2015 Apr 10;5(4):e303. doi: 10.1038/bcj.2015.14. Blood Cancer J. 2015. PMID: 25860294 Free PMC article.
PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
Singh AR, Joshi S, Zulcic M, Alcaraz M, Garlich JR, Morales GA, Cho YJ, Bao L, Levy ML, Newbury R, Malicki D, Messer K, Crawford J, Durden DL. Singh AR, et al. Among authors: Messer K. PLoS One. 2016 Mar 3;11(3):e0150836. doi: 10.1371/journal.pone.0150836. eCollection 2016. PLoS One. 2016. PMID: 26938241 Free PMC article.
PI3Kγ is a molecular switch that controls immune suppression.
Kaneda MM, Messer KS, Ralainirina N, Li H, Leem CJ, Gorjestani S, Woo G, Nguyen AV, Figueiredo CC, Foubert P, Schmid MC, Pink M, Winkler DG, Rausch M, Palombella VJ, Kutok J, McGovern K, Frazer KA, Wu X, Karin M, Sasik R, Cohen EE, Varner JA. Kaneda MM, et al. Among authors: Messer KS. Nature. 2016 Nov 17;539(7629):437-442. doi: 10.1038/nature19834. Epub 2016 Sep 19. Nature. 2016. PMID: 27642729 Free PMC article.
Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.
Zhang S, Zhang H, Ghia EM, Huang J, Wu L, Zhang J, Lam S, Lei Y, He J, Cui B, Widhopf GF 2nd, Yu J, Schwab R, Messer K, Jiang W, Parker BA, Carson DA, Kipps TJ. Zhang S, et al. Among authors: Messer K. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1370-1377. doi: 10.1073/pnas.1816262116. Epub 2019 Jan 8. Proc Natl Acad Sci U S A. 2019. PMID: 30622177 Free PMC article.
Publisher Correction: Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
Ando M, Saito Y, Xu G, Bui NQ, Medetgul-Ernar K, Pu M, Fisch K, Ren S, Sakai A, Fukusumi T, Liu C, Haft S, Pang J, Mark A, Gaykalova DA, Guo T, Favorov AV, Yegnasubramanian S, Fertig EJ, Ha P, Tamayo P, Yamasoba T, Ideker T, Messer K, Califano JA. Ando M, et al. Among authors: Messer K. Nat Commun. 2019 May 29;10(1):2415. doi: 10.1038/s41467-019-10557-7. Nat Commun. 2019. PMID: 31142745 Free PMC article.
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