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The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview.
Djupesland PG, Messina JC, Mahmoud RA. Djupesland PG, et al. Among authors: messina jc. Ther Deliv. 2014 Jun;5(6):709-33. doi: 10.4155/tde.14.41. Ther Deliv. 2014. PMID: 25090283 Review.
Breath powered nasal delivery: a new route to rapid headache relief.
Djupesland PG, Messina JC, Mahmoud RA. Djupesland PG, et al. Among authors: messina jc. Headache. 2013 Sep;53 Suppl 2:72-84. doi: 10.1111/head.12186. Headache. 2013. PMID: 24024605 Free PMC article. Review.
Accessing the brain: the nose may know the way.
Djupesland PG, Mahmoud RA, Messina JC. Djupesland PG, et al. Among authors: messina jc. J Cereb Blood Flow Metab. 2013 May;33(5):793-4. doi: 10.1038/jcbfm.2013.41. Epub 2013 Mar 13. J Cereb Blood Flow Metab. 2013. PMID: 23486291 Free PMC article. No abstract available.
NAVIGATE I: Randomized, Placebo-Controlled, Double-Blind Trial of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis With Nasal Polyps.
Sindwani R, Han JK, Soteres DF, Messina JC, Carothers JL, Mahmoud RA, Djupesland PG. Sindwani R, et al. Among authors: messina jc. Am J Rhinol Allergy. 2019 Jan;33(1):69-82. doi: 10.1177/1945892418810281. Epub 2018 Nov 27. Am J Rhinol Allergy. 2019. PMID: 30477309 Free PMC article. Clinical Trial.
NAVIGATE II: Randomized, double-blind trial of the exhalation delivery system with fluticasone for nasal polyposis.
Leopold DA, Elkayam D, Messina JC, Kosik-Gonzalez C, Djupesland PG, Mahmoud RA. Leopold DA, et al. Among authors: messina jc. J Allergy Clin Immunol. 2019 Jan;143(1):126-134.e5. doi: 10.1016/j.jaci.2018.06.010. Epub 2018 Jun 19. J Allergy Clin Immunol. 2019. PMID: 29928924 Clinical Trial.
AVP-825 breath-powered intranasal delivery system containing 22 mg sumatriptan powder vs 100 mg oral sumatriptan in the acute treatment of migraines (The COMPASS study): a comparative randomized clinical trial across multiple attacks.
Tepper SJ, Cady RK, Silberstein S, Messina J, Mahmoud RA, Djupesland PG, Shin P, Siffert J. Tepper SJ, et al. Among authors: messina j. Headache. 2015 May;55(5):621-35. doi: 10.1111/head.12583. Epub 2015 May 4. Headache. 2015. PMID: 25941016 Free PMC article. Clinical Trial.
EXHANCE-12: 1-year study of the exhalation delivery system with fluticasone (EDS-FLU) in chronic rhinosinusitis.
Palmer JN, Jacobson KW, Messina JC, Kosik-Gonzalez C, Djupesland PG, Mahmoud RA. Palmer JN, et al. Among authors: messina jc. Int Forum Allergy Rhinol. 2018 Jun 1;8(8):869-76. doi: 10.1002/alr.22141. Online ahead of print. Int Forum Allergy Rhinol. 2018. PMID: 29856520 Free PMC article.
A cross-sectional, population-based survey of U.S. adults with symptoms of chronic rhinosinusitis.
Palmer JN, Messina JC, Biletch R, Grosel K, Mahmoud RA. Palmer JN, et al. Among authors: messina jc. Allergy Asthma Proc. 2019 Jan 14;40(1):48-56. doi: 10.2500/aap.2019.40.4182. Allergy Asthma Proc. 2019. PMID: 30582496
The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain.
Ashburn MA, Slevin KA, Messina J, Xie F. Ashburn MA, et al. Among authors: messina j. Anesth Analg. 2011 Mar;112(3):693-702. doi: 10.1213/ANE.0b013e318209d320. Epub 2011 Feb 8. Anesth Analg. 2011. PMID: 21304148 Clinical Trial.
A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain.
Farrar JT, Messina J, Xie F, Portenoy RK. Farrar JT, et al. Among authors: messina j. Pain Med. 2010 Sep;11(9):1313-27. doi: 10.1111/j.1526-4637.2010.00939.x. Epub 2010 Aug 30. Pain Med. 2010. PMID: 20807345 Clinical Trial.
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