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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 1
1977 1
1978 2
1979 1
1985 1
1986 1
1987 2
1989 4
1990 3
1991 4
1992 3
1993 5
1994 4
1995 6
1997 4
1998 9
1999 14
2000 11
2001 13
2002 16
2003 15
2004 15
2005 20
2006 24
2007 21
2008 25
2009 20
2010 23
2011 17
2012 24
2013 29
2014 27
2015 32
2016 30
2017 30
2018 26
2019 28
2020 45
2021 37
2022 34
2023 26
2024 12

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594 results

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Page 1
Gut Microbiota and Cardiovascular Disease.
Witkowski M, Weeks TL, Hazen SL. Witkowski M, et al. Circ Res. 2020 Jul 31;127(4):553-570. doi: 10.1161/CIRCRESAHA.120.316242. Epub 2020 Jul 30. Circ Res. 2020. PMID: 32762536 Free PMC article. Review.
Fecal microbial community changes are associated with numerous disease states, including cardiovascular disease (CVD). However, such data are merely associative. ...We focus on microbiota and metaorganismal compounds/pathways, with specific attention paid to short-c …
Fecal microbial community changes are associated with numerous disease states, including cardiovascular disease (CVD). However …
Mitochondrial alterations in fatty liver diseases.
Fromenty B, Roden M. Fromenty B, et al. J Hepatol. 2023 Feb;78(2):415-429. doi: 10.1016/j.jhep.2022.09.020. Epub 2022 Oct 7. J Hepatol. 2023. PMID: 36209983 Free article. Review.
Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic exposure and excessive alcohol use, all of which have been shown to exert toxic effects on hepatic mitochondrial functionality and dynamics. ...Nevertheless, abn
Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic exposure and excessiv
Energy metabolism in the liver.
Rui L. Rui L. Compr Physiol. 2014 Jan;4(1):177-97. doi: 10.1002/cphy.c130024. Compr Physiol. 2014. PMID: 24692138 Free PMC article. Review.
In the fed state, glycolytic products are used to synthesize fatty acids through de novo lipogenesis. Long-chain fatty acids are incorporated into triacylglycerol, phospholipids, and/or cholesterol esters in hepatocytes. ...Fasting also promotes lipoly …
In the fed state, glycolytic products are used to synthesize fatty acids through de novo lipogenesis. Long-chain fatty
Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications.
Ren J, Wu NN, Wang S, Sowers JR, Zhang Y. Ren J, et al. Physiol Rev. 2021 Oct 1;101(4):1745-1807. doi: 10.1152/physrev.00030.2020. Epub 2021 May 5. Physiol Rev. 2021. PMID: 33949876 Free PMC article. Review.
To this point, epidemiological, clinical, and experimental evidence supports the existence of a unique disease entity termed "obesity cardiomyopathy," which develops independent of hypertension, coronary heart disease, and other heart diseases. ...Indeed, con …
To this point, epidemiological, clinical, and experimental evidence supports the existence of a unique disease entity termed "obesity …
Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans.
Pafili K, Roden M. Pafili K, et al. Mol Metab. 2021 Aug;50:101122. doi: 10.1016/j.molmet.2020.101122. Epub 2020 Nov 19. Mol Metab. 2021. PMID: 33220492 Free PMC article. Review.
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic steatohepatitis, NASH) and/or fibrosis in the absence of other causes of liver disease. …
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with increased lipid accumulation (steatosi …
The fructose survival hypothesis for obesity.
Johnson RJ, Lanaspa MA, Sanchez-Lozada LG, Tolan D, Nakagawa T, Ishimoto T, Andres-Hernando A, Rodriguez-Iturbe B, Stenvinkel P. Johnson RJ, et al. Philos Trans R Soc Lond B Biol Sci. 2023 Sep 11;378(1885):20220230. doi: 10.1098/rstb.2022.0230. Epub 2023 Jul 24. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 37482773 Free PMC article. Review.
The fructose survival hypothesis proposes that obesity and metabolic disorders may have developed from over-stimulation of an evolutionary-based biologic response (survival switch) that aims to protect animals in advance of crisis. ...We propose excessive fructose m …
The fructose survival hypothesis proposes that obesity and metabolic disorders may have developed from over-stimulation of an …
The Biochemistry and Physiology of Mitochondrial Fatty Acid beta-Oxidation and Its Genetic Disorders.
Houten SM, Violante S, Ventura FV, Wanders RJ. Houten SM, et al. Annu Rev Physiol. 2016;78:23-44. doi: 10.1146/annurev-physiol-021115-105045. Epub 2015 Oct 14. Annu Rev Physiol. 2016. PMID: 26474213 Review.
Mitochondrial fatty acid beta-oxidation (FAO) is the major pathway for the degradation of fatty acids and is essential for maintaining energy homeostasis in the human body. Fatty acids are a crucial energy source in the postabsorpt …
Mitochondrial fatty acid beta-oxidation (FAO) is the major pathway for the degradation of fatty acids and …
Cancer metabolism: a therapeutic perspective.
Martinez-Outschoorn UE, Peiris-Pagés M, Pestell RG, Sotgia F, Lisanti MP. Martinez-Outschoorn UE, et al. Nat Rev Clin Oncol. 2017 Jan;14(1):11-31. doi: 10.1038/nrclinonc.2016.60. Epub 2016 May 4. Nat Rev Clin Oncol. 2017. PMID: 27141887 Review.
In general, tumour cells metabolize glucose, lactate, pyruvate, hydroxybutyrate, acetate, glutamine, and fatty acids at much higher rates than their nontumour equivalents; however, the metabolic ecology of tumours is complex because they contain multiple m
In general, tumour cells metabolize glucose, lactate, pyruvate, hydroxybutyrate, acetate, glutamine, and fatty acids at much h …
Metabolites as regulators of insulin sensitivity and metabolism.
Yang Q, Vijayakumar A, Kahn BB. Yang Q, et al. Nat Rev Mol Cell Biol. 2018 Oct;19(10):654-672. doi: 10.1038/s41580-018-0044-8. Nat Rev Mol Cell Biol. 2018. PMID: 30104701 Free PMC article. Review.
The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited to impaired insulin signalling but also involves the complex interplay of multiple metabolic pathways. The analysis of large data sets generated by metabolomics and lipidomics has …
The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited to impaired insulin signalling but also involv …
Metabolic Myopathies.
Tarnopolsky MA. Tarnopolsky MA. Continuum (Minneap Minn). 2022 Dec 1;28(6):1752-1777. doi: 10.1212/CON.0000000000001182. Continuum (Minneap Minn). 2022. PMID: 36537979 Review.
Although some drugs and hormones can affect metabolism in skeletal muscle, this review will focus on the genetic metabolic myopathies. RECENT FINDINGS: Impairments in glycogenolysis/glycolysis (glycogen storage disease), fatty acid transport/oxidati
Although some drugs and hormones can affect metabolism in skeletal muscle, this review will focus on the genetic metabolic myopathies …
594 results