Metformin can inhibit Helicobacter pylori growth.
Future Microbiol. 2018.
PMID: 30421627
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Metformin can inhibit Helicobacter pylori growth.
Future Microbiol. 2018 Nov;13:1575-1583. doi: 10.2217/fmb-2018-0184. Epub 2018 Nov 13.
Future Microbiol. 2018.
PMID: 30421627
AIM: Helicobacter pylori infection is a worldwide infection, its eradication rates with conventional therapies have fallen to unacceptable levels. ...RESULTS: Helicobacter pylori survival and growth were decreased in presence of metformin …
AIM: Helicobacter pylori infection is a worldwide infection, its eradication rates with conventional therapies have fallen to …
Antibacterial and Immunoregulatory Effects of Metformin against Helicobacter pylori Infection in Rat Model.
Biomed Res Int. 2023 Nov 21;2023:5583286. doi: 10.1155/2023/5583286. eCollection 2023.
Biomed Res Int. 2023.
PMID: 38192437
Free PMC article.
INTRODUCTION: Helicobacter pylori (H. pylori) induces gastritis by stimulating Th17 cells and related cytokines. The aim of our study was to investigate the synergistic effect of metformin with amoxicillin as an antibiotic in inhibiting H. py …
INTRODUCTION: Helicobacter pylori (H. pylori) induces gastritis by stimulating Th17 cells and related cytokines. The ai …
Gastrointestinal tract organoids as novel tools in drug discovery.
Front Pharmacol. 2024 Aug 30;15:1463114. doi: 10.3389/fphar.2024.1463114. eCollection 2024.
Front Pharmacol. 2024.
PMID: 39281285
Free PMC article.
Review.
Organoids of GIT diseases, including inflammatory bowel disease, irritable bowel syndrome, necrotizing enterocolitis, and Helicobacter pylori infection, have been successfully constructed. These models have facilitated the study of the mechanisms and effects of vari …
Organoids of GIT diseases, including inflammatory bowel disease, irritable bowel syndrome, necrotizing enterocolitis, and Helicobacter …
Metformin attenuates synergic effect of diabetes mellitus and Helicobacter pylori infection on gastric cancer cells proliferation by suppressing PTEN expression.
J Cell Mol Med. 2021 May;25(10):4534-4542. doi: 10.1111/jcmm.15967. Epub 2021 Mar 24.
J Cell Mol Med. 2021.
PMID: 33760349
Free PMC article.
It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. Furthermore, diabetes mellitus (DM) may also promote the methylation status of PTEN, a tumour suppressor gene in gastric cancer (GC). It is intriguin …
It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. Furthermo …
RETRACTED: CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis.
Mol Cancer Res. 2019 Nov;17(11):2169-2183. doi: 10.1158/1541-7786.MCR-19-0181. Epub 2019 Aug 15.
Mol Cancer Res. 2019.
Retraction in:
Mol Cancer Res. 2024 Nov 1;22(11):1065. doi: 10.1158/1541-7786.MCR-24-0859.
PMID: 31416838
Free article.
Retracted.
Intestinal-type gastric cancer often results from Helicobacter pylori infection through intestinal metaplasia, a transdifferentiated premalignant phenotype. ...In a murine xenograft model, combining metformin or shCDX1 with cisplatin reduced tumor growth …
Intestinal-type gastric cancer often results from Helicobacter pylori infection through intestinal metaplasia, a transdifferen …
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