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Metformin can inhibit Helicobacter pylori growth.
Courtois S, Bénéjat L, Izotte J, Mégraud F, Varon C, Lehours P, Bessède E. Courtois S, et al. Future Microbiol. 2018 Nov;13:1575-1583. doi: 10.2217/fmb-2018-0184. Epub 2018 Nov 13. Future Microbiol. 2018. PMID: 30421627
AIM: Helicobacter pylori infection is a worldwide infection, its eradication rates with conventional therapies have fallen to unacceptable levels. ...RESULTS: Helicobacter pylori survival and growth were decreased in presence of metformin
AIM: Helicobacter pylori infection is a worldwide infection, its eradication rates with conventional therapies have fallen to …
Antibacterial and Immunoregulatory Effects of Metformin against Helicobacter pylori Infection in Rat Model.
Valadbeigi H, Khoshnood S, Negahdari B, Abdullah MA, Haddadi MH. Valadbeigi H, et al. Biomed Res Int. 2023 Nov 21;2023:5583286. doi: 10.1155/2023/5583286. eCollection 2023. Biomed Res Int. 2023. PMID: 38192437 Free PMC article.
INTRODUCTION: Helicobacter pylori (H. pylori) induces gastritis by stimulating Th17 cells and related cytokines. The aim of our study was to investigate the synergistic effect of metformin with amoxicillin as an antibiotic in inhibiting H. py
INTRODUCTION: Helicobacter pylori (H. pylori) induces gastritis by stimulating Th17 cells and related cytokines. The ai …
Metformin attenuates synergic effect of diabetes mellitus and Helicobacter pylori infection on gastric cancer cells proliferation by suppressing PTEN expression.
Lu H, Han X, Ren J, Ren K, Li Z, Zhang Q. Lu H, et al. J Cell Mol Med. 2021 May;25(10):4534-4542. doi: 10.1111/jcmm.15967. Epub 2021 Mar 24. J Cell Mol Med. 2021. PMID: 33760349 Free PMC article.
It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. ...It is intriguing to explore whether DM may strengthen the tumorigenic effect of H pylori (HP) by promoting the methylation of PTEN promoter …
It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. ...It is …
CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis.
Choi SI, Yoon C, Park MR, Lee D, Kook MC, Lin JX, Kang JH, Ashktorab H, Smoot DT, Yoon SS, Cho SJ. Choi SI, et al. Mol Cancer Res. 2019 Nov;17(11):2169-2183. doi: 10.1158/1541-7786.MCR-19-0181. Epub 2019 Aug 15. Mol Cancer Res. 2019. PMID: 31416838
Intestinal-type gastric cancer often results from Helicobacter pylori infection through intestinal metaplasia, a transdifferentiated premalignant phenotype. ...In a murine xenograft model, combining metformin or shCDX1 with cisplatin reduced tumor growth
Intestinal-type gastric cancer often results from Helicobacter pylori infection through intestinal metaplasia, a transdifferen …