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Metformin can inhibit Helicobacter pylori growth.
Courtois S, Bénéjat L, Izotte J, Mégraud F, Varon C, Lehours P, Bessède E. Courtois S, et al. Future Microbiol. 2018 Nov;13:1575-1583. doi: 10.2217/fmb-2018-0184. Epub 2018 Nov 13. Future Microbiol. 2018. PMID: 30421627
In this context we were interested in metformin, to determine its effect on H. pylori growth. MATERIALS & METHODS: Antimicrobial susceptibility tests and survival curves were performed in vitro and a H. pylori-infected mice model was used to determ …
In this context we were interested in metformin, to determine its effect on H. pylori growth. MATERIALS & METHODS: …
Metformin attenuates synergic effect of diabetes mellitus and Helicobacter pylori infection on gastric cancer cells proliferation by suppressing PTEN expression.
Lu H, Han X, Ren J, Ren K, Li Z, Zhang Q. Lu H, et al. J Cell Mol Med. 2021 May;25(10):4534-4542. doi: 10.1111/jcmm.15967. Epub 2021 Mar 24. J Cell Mol Med. 2021. PMID: 33760349 Free PMC article.
It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. ...It is intriguing to explore whether DM may strengthen the tumorigenic effect of H pylori (HP) by promoting the methylation of PTEN promoter …
It has been reported that CagA of Helicobacter pylori reduced PTEN expression by enhancing its promoter methylation. ...It is …
CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis.
Choi SI, Yoon C, Park MR, Lee D, Kook MC, Lin JX, Kang JH, Ashktorab H, Smoot DT, Yoon SS, Cho SJ. Choi SI, et al. Mol Cancer Res. 2019 Nov;17(11):2169-2183. doi: 10.1158/1541-7786.MCR-19-0181. Epub 2019 Aug 15. Mol Cancer Res. 2019. PMID: 31416838
Intestinal-type gastric cancer often results from Helicobacter pylori infection through intestinal metaplasia, a transdifferentiated premalignant phenotype. ...In a murine xenograft model, combining metformin or shCDX1 with cisplatin reduced tumor growth …
Intestinal-type gastric cancer often results from Helicobacter pylori infection through intestinal metaplasia, a transdifferen …