Methods to analyse composition and dynamics of macromolecular complexes.
Biochem Soc Trans. 2013.
PMID: 24059513
Review.
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Methods to analyse composition and dynamics of macromolecular complexes.
Biochem Soc Trans. 2013 Oct;41(5):1235-41. doi: 10.1042/BST20130153.
Biochem Soc Trans. 2013.
PMID: 24059513
Review.
Macromolecular complexes are involved in a broad spectrum of cellular processes including protein biosynthesis, protein secretion and degradation, metabolism, DNA replication and repair, and signal transduction along with other important biological processes. ...In …
Macromolecular complexes are involved in a broad spectrum of cellular processes including protein biosynthesis, protein secret …
Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes.
Bioengineered. 2022 Jun;13(6):14681-14718. doi: 10.1080/21655979.2022.2100863.
Bioengineered. 2022.
PMID: 35946342
Free PMC article.
Review.
This extract was chosen because of its high adaptability, which reflects its resolute genetic composition. The proactive roles of cyanobacteria, particularly in the medical field, have been discussed in this review, including the history, previous food and drug administrat …
This extract was chosen because of its high adaptability, which reflects its resolute genetic composition. The proactive roles of cya …
Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics.
Nat Neurosci. 2016 Feb;19(2):233-42. doi: 10.1038/nn.4198. Epub 2015 Dec 21.
Nat Neurosci. 2016.
PMID: 26691831
We used high-resolution functional proteomics to identify the building blocks of these receptors in the rodent brain. Our analyses revealed that native GABAB receptors are macromolecular complexes with defined architecture, but marked diversity in subunit …
We used high-resolution functional proteomics to identify the building blocks of these receptors in the rodent brain. Our analyses re …
Single-Cell Confinement Methods to Study Plant Cytoskeleton.
Methods Mol Biol. 2023;2604:63-75. doi: 10.1007/978-1-0716-2867-6_5.
Methods Mol Biol. 2023.
PMID: 36773225
For instance, when using microwells made of agarose, the composition of the well can be easily modified to analyze the impact of biochemical cues. When using microwells in a stiff polymer (NOA73), protoplasts can be pressurized, and the wall of the well can be coate …
For instance, when using microwells made of agarose, the composition of the well can be easily modified to analyze the impact …
Exploration of macromolecular phenotype of human skeletal muscle in diabetes using infrared spectroscopy.
Front Endocrinol (Lausanne). 2023 Dec 21;14:1308373. doi: 10.3389/fendo.2023.1308373. eCollection 2023.
Front Endocrinol (Lausanne). 2023.
PMID: 38189046
Free PMC article.
In tissue studies, conventional histochemical methods have several technical limitations and have been shown to inadequately characterise the biomolecular phenotype of skeletal muscle to provide a holistic view of the pathologically altered proportions of macromolecular …
In tissue studies, conventional histochemical methods have several technical limitations and have been shown to inadequately characte …
Label-free identification of protein aggregates using deep learning.
Nat Commun. 2023 Nov 28;14(1):7816. doi: 10.1038/s41467-023-43440-7.
Nat Commun. 2023.
PMID: 38016971
Free PMC article.
The fluorescent labels commonly used to visualize and monitor the dynamics of protein expression have been shown to alter the biophysical properties of proteins and the final ultrastructure, composition, and toxic properties of the formed aggregates. ...Our models a …
The fluorescent labels commonly used to visualize and monitor the dynamics of protein expression have been shown to alter the biophys …
Vicenin-2 reduces inflammation and apoptosis to relieve skin photoaging via suppressing GSK3β.
J Photochem Photobiol B. 2025 Mar;264:113117. doi: 10.1016/j.jphotobiol.2025.113117. Epub 2025 Feb 6.
J Photochem Photobiol B. 2025.
PMID: 39923642
This study aims to elucidate the molecular mechanisms of Vicenin-2 in treating photoaging through network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation. METHODS: We utilized PubChem, Swiss Target Prediction, and Target N …
This study aims to elucidate the molecular mechanisms of Vicenin-2 in treating photoaging through network pharmacology, molecular docking, m …
Combinatorial assembly and function of chromatin regulatory complexes.
Epigenomics. 2011 Oct;3(5):567-80. doi: 10.2217/epi.11.83.
Epigenomics. 2011.
PMID: 22126247
Review.
The introduction of new methods for genome-wide analyses of the chromatin state, together with the power of refined techniques for mass spectrometry and biochemistry, has provided an unprecedented view on the complexity of eukaryotic gene regulation. Chromatin struc …
The introduction of new methods for genome-wide analyses of the chromatin state, together with the power of refined techniques …
Orientation and property of fibers of the myodural bridge in humans.
Spine J. 2018 Jun;18(6):1081-1087. doi: 10.1016/j.spinee.2018.02.006. Epub 2018 Mar 15.
Spine J. 2018.
PMID: 29477753
STUDY DESIGN: Anatomical and histologic analyses of suboccipital structures that communicate with the SDM at the posterior atlanto-occipital or atlantoaxial interspaces were carried out. METHODS: Multiple histologic staining methods were used to evaluate the …
STUDY DESIGN: Anatomical and histologic analyses of suboccipital structures that communicate with the SDM at the posterior atlanto-oc …
Lipid and protein content profiling of isolated native autophagic vesicles.
EMBO Rep. 2022 Dec 6;23(12):e53065. doi: 10.15252/embr.202153065. Epub 2022 Oct 10.
EMBO Rep. 2022.
PMID: 36215690
Free PMC article.
Autophagy is responsible for clearance of an extensive portfolio of cargoes, which are sequestered into vesicles, called autophagosomes, and are delivered to lysosomes for degradation. The pathway is highly dynamic and responsive to several stress conditions. However, the …
Autophagy is responsible for clearance of an extensive portfolio of cargoes, which are sequestered into vesicles, called autophagosomes, and …
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