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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 2
1948 1
1952 1
1954 1
1955 2
1959 1
1960 1
1962 1
1963 2
1964 1
1965 1
1967 5
1968 3
1969 4
1970 5
1971 6
1972 10
1973 5
1974 10
1975 6
1976 4
1977 12
1978 8
1979 7
1980 11
1981 9
1982 10
1983 11
1984 8
1985 7
1986 10
1987 18
1988 11
1989 22
1990 29
1991 35
1992 27
1993 46
1994 53
1995 54
1996 57
1997 38
1998 42
1999 40
2000 61
2001 46
2002 39
2003 45
2004 55
2005 70
2006 66
2007 72
2008 83
2009 80
2010 83
2011 81
2012 90
2013 93
2014 105
2015 105
2016 113
2017 123
2018 124
2019 103
2020 128
2021 89
2022 78
2023 92
2024 116
2025 168
2026 92

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2,744 results

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Page 1
Administration of methylene blue in septic shock: pros and cons.
Arias-Ortiz J, Vincent JL. Arias-Ortiz J, et al. Crit Care. 2024 Feb 16;28(1):46. doi: 10.1186/s13054-024-04839-w. Crit Care. 2024. PMID: 38365828 Free PMC article. Review.
Septic shock typically requires the administration of vasopressors. Adrenergic agents remain the first choice, namely norepinephrine. ...The use of non-selective NO synthase inhibitors has been of questionable benefit. Methylene blue, an inhibitor of soluble …
Septic shock typically requires the administration of vasopressors. Adrenergic agents remain the first choice, namely norepinephrine. …
The use of methylene blue in adult patients with septic shock: a systematic review and meta-analysis.
Ng KT, Kwok PE, Lim WE, Teoh WY, Hasan MS, Zainal Abidin MF. Ng KT, et al. Braz J Anesthesiol. 2025 Jan-Feb;75(1):844580. doi: 10.1016/j.bjane.2024.844580. Epub 2024 Nov 29. Braz J Anesthesiol. 2025. PMID: 39615751 Free PMC article.
OBJECTIVES: Methylene blue exerts its vasopressor properties by inhibiting nitric oxide-mediated vasodilation. Recent studies have advocated the use of methylene blue as a rescue therapy for patients with septic shock. The primary aim was to investigat …
OBJECTIVES: Methylene blue exerts its vasopressor properties by inhibiting nitric oxide-mediated vasodilation. Recent studies …
Prophylactic Administration with Methylene Blue Improves Hemodynamic Stabilization During Obstructive Jaundice-Related Diseases' Operation: a Blinded Randomized Controlled Trial.
Huang J, Gao X, Wang M, Yang Z, Xiang L, Li Y, Yi B, Gu J, Wen J, Lu K, Zhao H, Ma D, Chen L, Ning J. Huang J, et al. J Gastrointest Surg. 2023 Sep;27(9):1837-1845. doi: 10.1007/s11605-022-05499-3. Epub 2023 Apr 26. J Gastrointest Surg. 2023. PMID: 37101089 Free PMC article. Clinical Trial.
PATIENTS: Seventy patients were enrolled in the study and randomly assigned to receive either methylene blue or control (n = 35/group). RESULTS: Fewer patients received noradrenaline in the methylene blue group when compared with the control group (13/ …
PATIENTS: Seventy patients were enrolled in the study and randomly assigned to receive either methylene blue or control (n = 3 …
Methylene-blue-associated encephalopathy.
Sweet G, Standiford SB. Sweet G, et al. J Am Coll Surg. 2007 Mar;204(3):454-8. doi: 10.1016/j.jamcollsurg.2006.12.030. J Am Coll Surg. 2007. PMID: 17324781 Review. No abstract available.
Review and drug therapy implications of glucose-6-phosphate dehydrogenase deficiency.
Belfield KD, Tichy EM. Belfield KD, et al. Am J Health Syst Pharm. 2018 Feb 1;75(3):97-104. doi: 10.2146/ajhp160961. Epub 2018 Jan 5. Am J Health Syst Pharm. 2018. PMID: 29305344 Review.
When clinically feasible, rasburicase, primaquine, dapsone, pegloticase, and methylene blue should not be used until a G6PD diagnostic test has been performed....
When clinically feasible, rasburicase, primaquine, dapsone, pegloticase, and methylene blue should not be used until a G6PD di …
Methylene blue: NO panacea.
Schreiber MD. Schreiber MD. J Pediatr. 1996 Dec;129(6):790-3. doi: 10.1016/s0022-3476(96)70020-3. J Pediatr. 1996. PMID: 8969718 Review. No abstract available.
How worthwhile is methylene blue as a treatment of malaria?
Müller O, Lu G, Jahn A, Mockenhaupt FP. Müller O, et al. Expert Rev Anti Infect Ther. 2019 Jul;17(7):471-473. doi: 10.1080/14787210.2019.1634545. Epub 2019 Jun 25. Expert Rev Anti Infect Ther. 2019. PMID: 31237457 No abstract available.
[Methylene blue].
Kiyota K. Kiyota K. Chudoku Kenkyu. 2008 Oct;21(4):367-72. Chudoku Kenkyu. 2008. PMID: 19069129 Review. Japanese. No abstract available.
Hydroxocobalamin Versus Methylene Blue for Treatment of Vasoplegic Shock Following Cardiopulmonary Bypass: A Systematic Review and Meta-analysis.
Cadd M, Watson U, Kilpatrick T, Hardy B, Gallop L, Gerard A, Cabaret C. Cadd M, et al. J Cardiothorac Vasc Anesth. 2024 Dec;38(12):3188-3199. doi: 10.1053/j.jvca.2024.09.135. Epub 2024 Oct 5. J Cardiothorac Vasc Anesth. 2024. PMID: 39438181
OBJECTIVES: To summarize the evidence of the hemodynamic effects and vasopressor requirements of adult cardiac surgery patients with vasoplegic shock treated with hydroxocobalamin or methylene blue. DESIGN: Systematic review and meta-analysis. SETTING: Multi-institu …
OBJECTIVES: To summarize the evidence of the hemodynamic effects and vasopressor requirements of adult cardiac surgery patients with vasople …
Spectrophotometric analysis of purple urine secondary to methylene blue and hydroxocobalamin co-administration.
Hardin J, Galust H, Clark RF, Ly B, Suhandynata RT. Hardin J, et al. J Nephrol. 2024 Mar;37(2):491-494. doi: 10.1007/s40620-023-01769-8. Epub 2023 Aug 29. J Nephrol. 2024. PMID: 37644365 Free PMC article.
BACKGROUND: The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-administration is a rare clinical entity that has not been fully elucidated. ...CONCLUSION: Purple urine secondary to methylene blue …
BACKGROUND: The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-admini …
2,744 results