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4,679 results

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Page 1
Methysergide.
Silberstein SD. Silberstein SD. Cephalalgia. 1998 Sep;18(7):421-35. doi: 10.1046/j.1468-2982.1998.1807421.x. Cephalalgia. 1998. PMID: 9793694 Review.
Methysergide is a semisynthetic ergot alkaloid ergometrine derivative, introduced in pharmacotherapy for migraine prophylaxis as a specific serotonin (5HT) receptor antagonist. Methysergide is not just a 5HT2 antagonist, it is also a 5HT1 agonist. Open and controlle …
Methysergide is a semisynthetic ergot alkaloid ergometrine derivative, introduced in pharmacotherapy for migraine prophylaxis as a sp …
METHYSERGIDE.
MARSDEN JP. MARSDEN JP. Br Med J. 1964 Sep 12;2(5410):677. Br Med J. 1964. PMID: 14171102 Free PMC article. No abstract available.
History of methysergide in migraine.
Koehler PJ, Tfelt-Hansen PC. Koehler PJ, et al. Cephalalgia. 2008 Nov;28(11):1126-35. doi: 10.1111/j.1468-2982.2008.01648.x. Epub 2008 Jul 15. Cephalalgia. 2008. PMID: 18644039 Review.
This finding provided an incentive for the development of sumatriptan. Bredberg et al. showed that methysergide is probably a prodrug for its active metabolite methylergometrine. Whereas methysergide is 'a clean drug', methylergometrine is 'a relatively dirty drug' …
This finding provided an incentive for the development of sumatriptan. Bredberg et al. showed that methysergide is probably a prodrug …
Dihydroergotamine, ergotamine, methysergide and sumatriptan - basic science in relation to migraine treatment.
Dahlöf C, Maassen Van Den Brink A. Dahlöf C, et al. Headache. 2012 Apr;52(4):707-14. doi: 10.1111/j.1526-4610.2012.02124.x. Epub 2012 Mar 22. Headache. 2012. PMID: 22444161 Free article. Review.
The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5-HT(1B) , 5-HT(1D) , and 5-HT(1F) receptors. Ergotamine, dihydroergotamine, and methysergide, as well as the "triptan" sumatriptan, ar …
The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5- …
Methysergide in mania.
Dewhurst WG. Dewhurst WG. Nature. 1968 Aug 3;219(5153):506-7. doi: 10.1038/219506b0. Nature. 1968. PMID: 4875779 Clinical Trial. No abstract available.
Methysergide and retroperitoneal fibrosis.
Reimund E. Reimund E. Lancet. 1987 Feb 21;1(8530):443. doi: 10.1016/s0140-6736(87)90140-1. Lancet. 1987. PMID: 2880233 No abstract available.
Clinical pharmacokinetics of ergotamine, dihydroergotamine, ergotoxine, bromocriptine, methysergide, and lergotrile.
Kanto J. Kanto J. Int J Clin Pharmacol Ther Toxicol. 1983 Mar;21(3):135-42. Int J Clin Pharmacol Ther Toxicol. 1983. PMID: 6133838 Review.
The clinical pharmacokinetics of ergotamine, dihydroergotamine, ergotoxine, bromocriptine, methysergide, and lergotrile are reviewed. Generally the new radioimmunoassay methods have partially resolved the problems involved in determining some of these ergot derivatives in …
The clinical pharmacokinetics of ergotamine, dihydroergotamine, ergotoxine, bromocriptine, methysergide, and lergotrile are reviewed. …
Methysergide.
Graham JR. Graham JR. Practitioner. 1967 Feb;198(184):302-11. Practitioner. 1967. PMID: 6038987 No abstract available.
[Methysergide].
Kerckhoffs HP. Kerckhoffs HP. Pharm Weekbl. 1967 May 5;102(18):385-6. Pharm Weekbl. 1967. PMID: 6044088 Dutch. No abstract available.
Methysergide in the treatment of narcolepsy.
Wyler AR, Wilkus RJ, Troupin AS. Wyler AR, et al. Arch Neurol. 1975 Apr;32(4):265-8. doi: 10.1001/archneur.1975.00490460081012. Arch Neurol. 1975. PMID: 164849
Five patients with narcolepsy (four with the allied symptom of cataplexy) were treated with the serotonin antagonist methysergide. All patients had as good control of their sleep attacks while on methysergide therapy as on a control period of dextroamphetamine thera …
Five patients with narcolepsy (four with the allied symptom of cataplexy) were treated with the serotonin antagonist methysergide. Al …
4,679 results