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Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
Santiago L, Castro M, Sanz-Pamplona R, Garzón M, Ramirez-Labrada A, Tapia E, Moreno V, Layunta E, Gil-Gómez G, Garrido M, Peña R, Lanuza PM, Comas L, Jaime-Sanchez P, Uranga-Murillo I, Del Campo R, Pelegrín P, Camerer E, Martínez-Lostao L, Muñoz G, Uranga JA, Alcalde A, Galvez EM, Ferrandez A, Bird PI, Metkar S, Arias MA, Pardo J. Santiago L, et al. Among authors: metkar s. Cell Rep. 2020 Jul 7;32(1):107847. doi: 10.1016/j.celrep.2020.107847. Cell Rep. 2020. PMID: 32640217 Free article.
Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.
Santiago L, Menaa C, Arias M, Martin P, Jaime-Sánchez P, Metkar S, Comas L, Erill N, Gonzalez-Rumayor V, Esser E, Galvez EM, Raja S, Simon MM, Sprague SM, Gabay C, Martinez-Lostao L, Pardo J, Froelich CJ. Santiago L, et al. Among authors: metkar s. Arthritis Rheumatol. 2017 Feb;69(2):320-334. doi: 10.1002/art.39857. Arthritis Rheumatol. 2017. PMID: 27598995
In memoriam: Prof Christopher J Froelich (1951-2015).
Metkar SS, Pardo J, Anderluh G, Salvesen G, Trapani JA, Simon MM. Metkar SS, et al. Cell Death Differ. 2016 Jan;23(1):3-4. doi: 10.1038/cdd.2015.141. Cell Death Differ. 2016. PMID: 26639556 Free PMC article. No abstract available.
Human and mouse granzyme A induce a proinflammatory cytokine response.
Metkar SS, Menaa C, Pardo J, Wang B, Wallich R, Freudenberg M, Kim S, Raja SM, Shi L, Simon MM, Froelich CJ. Metkar SS, et al. Immunity. 2008 Nov 14;29(5):720-33. doi: 10.1016/j.immuni.2008.08.014. Epub 2008 Oct 23. Immunity. 2008. PMID: 18951048 Free article.
Perforin rapidly induces plasma membrane phospholipid flip-flop.
Metkar SS, Wang B, Catalan E, Anderluh G, Gilbert RJ, Pardo J, Froelich CJ. Metkar SS, et al. PLoS One. 2011;6(9):e24286. doi: 10.1371/journal.pone.0024286. Epub 2011 Sep 12. PLoS One. 2011. PMID: 21931672 Free PMC article.
56 results