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eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies.
Alain T, Morita M, Fonseca BD, Yanagiya A, Siddiqui N, Bhat M, Zammit D, Marcus V, Metrakos P, Voyer LA, Gandin V, Liu Y, Topisirovic I, Sonenberg N. Alain T, et al. Among authors: metrakos p. Cancer Res. 2012 Dec 15;72(24):6468-76. doi: 10.1158/0008-5472.CAN-12-2395. Epub 2012 Oct 24. Cancer Res. 2012. PMID: 23100465
Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells.
Bhat M, Yanagiya A, Graber T, Razumilava N, Bronk S, Zammit D, Zhao Y, Zakaria C, Metrakos P, Pollak M, Sonenberg N, Gores G, Jaramillo M, Morita M, Alain T. Bhat M, et al. Among authors: metrakos p. Oncotarget. 2016 Jul 18;8(31):50542-50556. doi: 10.18632/oncotarget.10671. eCollection 2017 Aug 1. Oncotarget. 2016. PMID: 28881582 Free PMC article.
Liver transplantation for metastases from a bile duct carcinoid.
Tzimas GN, Vali K, Deschênes M, Marcus VA, Barkun JS, Tchervenkov JI, Metrakos PP. Tzimas GN, et al. Among authors: metrakos pp. HPB (Oxford). 2006;8(1):67-8. doi: 10.1080/13651820600573170. HPB (Oxford). 2006. PMID: 18333243 Free PMC article.
Decreased PCSK9 expression in human hepatocellular carcinoma.
Bhat M, Skill N, Marcus V, Deschenes M, Tan X, Bouteaud J, Negi S, Awan Z, Aikin R, Kwan J, Amre R, Tabaries S, Hassanain M, Seidah NG, Maluccio M, Siegel P, Metrakos P. Bhat M, et al. Among authors: metrakos p. BMC Gastroenterol. 2015 Dec 16;15:176. doi: 10.1186/s12876-015-0371-6. BMC Gastroenterol. 2015. PMID: 26674961 Free PMC article.
205 results