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30 results
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Stochastic switching as a survival strategy in fluctuating environments.
Acar M, Mettetal JT, van Oudenaarden A. Acar M, et al. Among authors: mettetal jt. Nat Genet. 2008 Apr;40(4):471-5. doi: 10.1038/ng.110. Epub 2008 Mar 23. Nat Genet. 2008. PMID: 18362885
A systems-level analysis of perfect adaptation in yeast osmoregulation.
Muzzey D, Gómez-Uribe CA, Mettetal JT, van Oudenaarden A. Muzzey D, et al. Among authors: mettetal jt. Cell. 2009 Jul 10;138(1):160-71. doi: 10.1016/j.cell.2009.04.047. Cell. 2009. PMID: 19596242 Free PMC article.
The frequency dependence of osmo-adaptation in Saccharomyces cerevisiae.
Mettetal JT, Muzzey D, Gómez-Uribe C, van Oudenaarden A. Mettetal JT, et al. Science. 2008 Jan 25;319(5862):482-4. doi: 10.1126/science.1151582. Science. 2008. PMID: 18218902 Free PMC article.
Heritable stochastic switching revealed by single-cell genealogy.
Kaufmann BB, Yang Q, Mettetal JT, van Oudenaarden A. Kaufmann BB, et al. Among authors: mettetal jt. PLoS Biol. 2007 Sep;5(9):e239. doi: 10.1371/journal.pbio.0050239. PLoS Biol. 2007. PMID: 17803359 Free PMC article.
Predicting stochastic gene expression dynamics in single cells.
Mettetal JT, Muzzey D, Pedraza JM, Ozbudak EM, van Oudenaarden A. Mettetal JT, et al. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7304-9. doi: 10.1073/pnas.0509874103. Epub 2006 Apr 28. Proc Natl Acad Sci U S A. 2006. PMID: 16648266 Free PMC article.
Microbiology. Necessary noise.
Mettetal JT, van Oudenaarden A. Mettetal JT, et al. Science. 2007 Jul 27;317(5837):463-4. doi: 10.1126/science.1146747. Science. 2007. PMID: 17656711 No abstract available.
Cellular asymmetry and individuality in directional sensing.
Samadani A, Mettetal J, van Oudenaarden A. Samadani A, et al. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11549-54. doi: 10.1073/pnas.0601909103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864788 Free PMC article.
Systems Pharmacology Model of Gastrointestinal Damage Predicts Species Differences and Optimizes Clinical Dosing Schedules.
Shankaran H, Cronin A, Barnes J, Sharma P, Tolsma J, Jasper P, Mettetal JT. Shankaran H, et al. Among authors: mettetal jt. CPT Pharmacometrics Syst Pharmacol. 2018 Jan;7(1):26-33. doi: 10.1002/psp4.12255. Epub 2017 Dec 6. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 28941225 Free PMC article.
Dose schedule optimization and the pharmacokinetic driver of neutropenia.
Patel M, Palani S, Chakravarty A, Yang J, Shyu WC, Mettetal JT. Patel M, et al. Among authors: mettetal jt. PLoS One. 2014 Oct 31;9(10):e109892. doi: 10.1371/journal.pone.0109892. eCollection 2014. PLoS One. 2014. PMID: 25360756 Free PMC article.
Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction.
Gebremichael Y, Lu J, Shankaran H, Helmlinger G, Mettetal J, Hallow KM. Gebremichael Y, et al. Toxicol Sci. 2018 Mar 1;162(1):200-211. doi: 10.1093/toxsci/kfx239. Toxicol Sci. 2018. PMID: 29126144
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