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Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease.
de Zeeuw D, Akizawa T, Audhya P, Bakris GL, Chin M, Christ-Schmidt H, Goldsberry A, Houser M, Krauth M, Lambers Heerspink HJ, McMurray JJ, Meyer CJ, Parving HH, Remuzzi G, Toto RD, Vaziri ND, Wanner C, Wittes J, Wrolstad D, Chertow GM; BEACON Trial Investigators. de Zeeuw D, et al. Among authors: meyer cj. N Engl J Med. 2013 Dec 26;369(26):2492-503. doi: 10.1056/NEJMoa1306033. Epub 2013 Nov 9. N Engl J Med. 2013. PMID: 24206459 Free PMC article. Clinical Trial.
Bardoxolone methyl and kidney function in CKD with type 2 diabetes.
Pergola PE, Raskin P, Toto RD, Meyer CJ, Huff JW, Grossman EB, Krauth M, Ruiz S, Audhya P, Christ-Schmidt H, Wittes J, Warnock DG; BEAM Study Investigators. Pergola PE, et al. Among authors: meyer cj. N Engl J Med. 2011 Jul 28;365(4):327-36. doi: 10.1056/NEJMoa1105351. Epub 2011 Jun 24. N Engl J Med. 2011. PMID: 21699484 Free article. Clinical Trial.
Bardoxolone methyl decreases megalin and activates nrf2 in the kidney.
Reisman SA, Chertow GM, Hebbar S, Vaziri ND, Ward KW, Meyer CJ. Reisman SA, et al. Among authors: meyer cj. J Am Soc Nephrol. 2012 Oct;23(10):1663-73. doi: 10.1681/ASN.2012050457. Epub 2012 Aug 2. J Am Soc Nephrol. 2012. PMID: 22859857 Free PMC article.
Rationale and trial design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: the Occurrence of Renal Events (BEACON).
de Zeeuw D, Akizawa T, Agarwal R, Audhya P, Bakris GL, Chin M, Krauth M, Lambers Heerspink HJ, Meyer CJ, McMurray JJ, Parving HH, Pergola PE, Remuzzi G, Toto RD, Vaziri ND, Wanner C, Warnock DG, Wittes J, Chertow GM. de Zeeuw D, et al. Among authors: meyer cj. Am J Nephrol. 2013;37(3):212-22. doi: 10.1159/000346948. Epub 2013 Feb 28. Am J Nephrol. 2013. PMID: 23467003 Free article. Clinical Trial.
Baseline characteristics in the Bardoxolone methyl EvAluation in patients with Chronic kidney disease and type 2 diabetes mellitus: the Occurrence of renal eveNts (BEACON) trial.
Lambers Heerspink HJ, Chertow GM, Akizawa T, Audhya P, Bakris GL, Goldsberry A, Krauth M, Linde P, McMurray JJ, Meyer CJ, Parving HH, Remuzzi G, Christ-Schmidt H, Toto RD, Vaziri ND, Wanner C, Wittes J, Wrolstad D, de Zeeuw D. Lambers Heerspink HJ, et al. Among authors: meyer cj. Nephrol Dial Transplant. 2013 Nov;28(11):2841-50. doi: 10.1093/ndt/gft445. Nephrol Dial Transplant. 2013. PMID: 24169612 Clinical Trial.
Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
Chin MP, Reisman SA, Bakris GL, O'Grady M, Linde PG, McCullough PA, Packham D, Vaziri ND, Ward KW, Warnock DG, Meyer CJ. Chin MP, et al. Among authors: meyer cj. Am J Nephrol. 2014;39(6):499-508. doi: 10.1159/000362906. Epub 2014 Jun 3. Am J Nephrol. 2014. PMID: 24903467 Free article. Clinical Trial.
Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
Chin MP, Wrolstad D, Bakris GL, Chertow GM, de Zeeuw D, Goldsberry A, Linde PG, McCullough PA, McMurray JJ, Wittes J, Meyer CJ. Chin MP, et al. Among authors: meyer cj. J Card Fail. 2014 Dec;20(12):953-8. doi: 10.1016/j.cardfail.2014.10.001. Epub 2014 Oct 13. J Card Fail. 2014. PMID: 25307295 Free article. Clinical Trial.
159 results