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Characterization of pre-analytical sample handling effects on a panel of Alzheimer's disease-related blood-based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group.
Verberk IMW, Misdorp EO, Koelewijn J, Ball AJ, Blennow K, Dage JL, Fandos N, Hansson O, Hirtz C, Janelidze S, Kang S, Kirmess K, Kindermans J, Lee R, Meyer MR, Shan D, Shaw LM, Waligorska T, West T, Zetterberg H, Edelmayer RM, Teunissen CE. Verberk IMW, et al. Among authors: meyer mr. Alzheimers Dement. 2022 Aug;18(8):1484-1497. doi: 10.1002/alz.12510. Epub 2021 Nov 29. Alzheimers Dement. 2022. PMID: 34845818 Free PMC article.
A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis.
West T, Kirmess KM, Meyer MR, Holubasch MS, Knapik SS, Hu Y, Contois JH, Jackson EN, Harpstrite SE, Bateman RJ, Holtzman DM, Verghese PB, Fogelman I, Braunstein JB, Yarasheski KE. West T, et al. Among authors: meyer mr. Mol Neurodegener. 2021 May 1;16(1):30. doi: 10.1186/s13024-021-00451-6. Mol Neurodegener. 2021. PMID: 33933117 Free PMC article.
The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis.
Kirmess KM, Meyer MR, Holubasch MS, Knapik SS, Hu Y, Jackson EN, Harpstrite SE, Verghese PB, West T, Fogelman I, Braunstein JB, Yarasheski KE, Contois JH. Kirmess KM, et al. Among authors: meyer mr. Clin Chim Acta. 2021 Aug;519:267-275. doi: 10.1016/j.cca.2021.05.011. Epub 2021 May 17. Clin Chim Acta. 2021. PMID: 34015303 Free PMC article.
Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment.
Hu Y, Kirmess KM, Meyer MR, Rabinovici GD, Gatsonis C, Siegel BA, Whitmer RA, Apgar C, Hanna L, Kanekiyo M, Kaplow J, Koyama A, Verbel D, Holubasch MS, Knapik SS, Connor J, Contois JH, Jackson EN, Harpstrite SE, Bateman RJ, Holtzman DM, Verghese PB, Fogelman I, Braunstein JB, Yarasheski KE, West T. Hu Y, et al. Among authors: meyer mr. JAMA Netw Open. 2022 Apr 1;5(4):e228392. doi: 10.1001/jamanetworkopen.2022.8392. JAMA Netw Open. 2022. PMID: 35446396 Free PMC article.
Comparison of plasma and CSF biomarkers in predicting cognitive decline.
Aschenbrenner AJ, Li Y, Henson RL, Volluz K, Hassenstab J, Verghese P, West T, Meyer MR, Kirmess KM, Fagan AM, Xiong C, Holtzman D, Morris JC, Bateman RJ, Schindler SE. Aschenbrenner AJ, et al. Among authors: meyer mr. Ann Clin Transl Neurol. 2022 Nov;9(11):1739-1751. doi: 10.1002/acn3.51670. Epub 2022 Oct 2. Ann Clin Transl Neurol. 2022. PMID: 36183195 Free PMC article.
Independent study demonstrates amyloid probability score accurately indicates amyloid pathology.
Fogelman I, West T, Braunstein JB, Verghese PB, Kirmess KM, Meyer MR, Contois JH, Shobin E, Ferber KL, Gagnon J, Rubel CE, Graham D, Bateman RJ, Holtzman DM, Huang S, Yu J, Yang S, Yarasheski KE. Fogelman I, et al. Among authors: meyer mr. Ann Clin Transl Neurol. 2023 May;10(5):765-778. doi: 10.1002/acn3.51763. Epub 2023 Mar 28. Ann Clin Transl Neurol. 2023. PMID: 36975407 Free PMC article.
Plasma Aβ42/40 and cognitive variability are associated with cognitive function in Black Americans: Findings from the AA-FAIM cohort.
Fischer B, Van Hulle CA, Langhough R, Norton D, Zuelsdorff M, Gooding DC, Wyman MF, Johnson A, Lambrou N, James T, Bouges S, Carter FP, Salazar H, Kirmess K, Holubasch M, Meyer M, Venkatesh V, West T, Verghese P, Yarasheski K, Carlsson CM, Johnson SC, Asthana S, Gleason CE. Fischer B, et al. Alzheimers Dement (N Y). 2023 Sep 25;9(3):e12414. doi: 10.1002/trc2.12414. eCollection 2023 Jul-Sep. Alzheimers Dement (N Y). 2023. PMID: 37752907 Free PMC article.
Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Rissman RA, Langford O, Raman R, Donohue MC, Abdel-Latif S, Meyer MR, Wente-Roth T, Kirmess KM, Ngolab J, Winston CN, Jimenez-Maggiora G, Rafii MS, Sachdev P, West T, Yarasheski KE, Braunstein JB, Irizarry M, Johnson KA, Aisen PS, Sperling RA; AHEAD 3-45 Study team. Rissman RA, et al. Among authors: meyer mr. Alzheimers Dement. 2024 Feb;20(2):1214-1224. doi: 10.1002/alz.13542. Epub 2023 Nov 6. Alzheimers Dement. 2024. PMID: 37932961 Free PMC article.
Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset.
Li Y, Yen D, Hendrix RD, Gordon BA, Dlamini S, Barthélemy NR, Aschenbrenner AJ, Henson RL, Herries EM, Volluz K, Kirmess K, Eastwood S, Meyer M, Heller M, Jarrett L, McDade E, Holtzman DM, Benzinger TLS, Morris JC, Bateman RJ, Xiong C, Schindler SE. Li Y, et al. Ann Neurol. 2024 Feb 24. doi: 10.1002/ana.26891. Online ahead of print. Ann Neurol. 2024. PMID: 38400792
The Bio-Hermes Study: Biomarker database developed to investigate blood-based and digital biomarkers in community-based, diverse populations clinically screened for Alzheimer's disease.
Mohs RC, Beauregard D, Dwyer J, Gaudioso J, Bork J, MaGee-Rodgers T, Key MN, Kerwin DR, Hughes L, Cordell CB; Bio-Hermes Collaborative Group. Mohs RC, et al. Alzheimers Dement. 2024 Feb 28. doi: 10.1002/alz.13722. Online ahead of print. Alzheimers Dement. 2024. PMID: 38415908
386 results