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LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.
Mi S, Lee X, Shao Z, Thill G, Ji B, Relton J, Levesque M, Allaire N, Perrin S, Sands B, Crowell T, Cate RL, McCoy JM, Pepinsky RB. Mi S, et al. Nat Neurosci. 2004 Mar;7(3):221-8. doi: 10.1038/nn1188. Epub 2004 Feb 15. Nat Neurosci. 2004. PMID: 14966521
LINGO-1 negatively regulates myelination by oligodendrocytes.
Mi S, Miller RH, Lee X, Scott ML, Shulag-Morskaya S, Shao Z, Chang J, Thill G, Levesque M, Zhang M, Hession C, Sah D, Trapp B, He Z, Jung V, McCoy JM, Pepinsky RB. Mi S, et al. Nat Neurosci. 2005 Jun;8(6):745-51. doi: 10.1038/nn1460. Epub 2005 May 15. Nat Neurosci. 2005. PMID: 15895088
Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models.
Inoue H, Lin L, Lee X, Shao Z, Mendes S, Snodgrass-Belt P, Sweigard H, Engber T, Pepinsky B, Yang L, Beal MF, Mi S, Isacson O. Inoue H, et al. Among authors: mi s. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14430-5. doi: 10.1073/pnas.0700901104. Epub 2007 Aug 28. Proc Natl Acad Sci U S A. 2007. PMID: 17726113 Free PMC article.
Dissecting demyelination.
Miller RH, Mi S. Miller RH, et al. Among authors: mi s. Nat Neurosci. 2007 Nov;10(11):1351-4. doi: 10.1038/nn1995. Nat Neurosci. 2007. PMID: 17965654 Review.
508 results