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Intravenous fosfomycin for the treatment of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae in critically ill patients: a prospective evaluation.
Michalopoulos A, Virtzili S, Rafailidis P, Chalevelakis G, Damala M, Falagas ME. Michalopoulos A, et al. Clin Microbiol Infect. 2010 Feb;16(2):184-6. doi: 10.1111/j.1469-0691.2009.02921.x. Epub 2009 Aug 20. Clin Microbiol Infect. 2010. PMID: 19694767 Clinical Trial.
Intensive care unit (ICU)-acquired infections as a result of multidrug-resistant Gram-negative pathogens remain a serious problem in critically ill patients. ...Intravenous fosfomycin may be a beneficial and safe adjunctive treatment in the management of life …
Intensive care unit (ICU)-acquired infections as a result of multidrug-resistant Gram-negative pathogens remain a serious prob …
Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317].
Georgopoulos D, Matamis D, Routsi C, Michalopoulos A, Maggina N, Dimopoulos G, Zakynthinos E, Nakos G, Thomopoulos G, Mandragos K, Maniatis A; Critical Care Clinical Trials Greek Group. Georgopoulos D, et al. Among authors: michalopoulos a. Crit Care. 2005 Oct 5;9(5):R508-15. doi: 10.1186/cc3786. Epub 2005 Aug 5. Crit Care. 2005. PMID: 16277712 Free PMC article. Clinical Trial.
METHOD: This was a prospective, randomized, multicentre trial. A total of 13 intensive care units participated, and a total of 148 patients who met eligibility criteria were enrolled. ...The mean increase in Hct was significantly greater in group B than in gr …
METHOD: This was a prospective, randomized, multicentre trial. A total of 13 intensive care units participated, and a t …
Usual interstitial pneumonia associated with cytomegalovirus infection after percutaneous transluminal coronary angioplasty.
Rizos M, Falagas ME, Tsiodras S, Betsou A, Foukas P, Michalopoulos A. Rizos M, et al. Among authors: michalopoulos a. Eur J Clin Microbiol Infect Dis. 2004 Nov;23(11):848-50. doi: 10.1007/s10096-004-1220-7. Epub 2004 Oct 8. Eur J Clin Microbiol Infect Dis. 2004. PMID: 15480886
An unusual case of cytomegalovirus (CMV) pneumonia in a diabetic patient is presented. The diagnosis was based on typical histopathological findings including intranuclear inclusion bodies combined with molecular identification of CMV in tissue specimens. The possibility o …
An unusual case of cytomegalovirus (CMV) pneumonia in a diabetic patient is presented. The diagnosis was based on typical histopathol …
Performance status (PS): a simple predictor of short-term outcome of cancer patients with solid tumors admitted to the intensive care unit (ICU).
Christodoulou C, Rizos M, Galani E, Rellos K, Skarlos DV, Michalopoulos A. Christodoulou C, et al. Among authors: michalopoulos a. Anticancer Res. 2007 Jul-Aug;27(4C):2945-8. Anticancer Res. 2007. PMID: 17695475
PATIENTS AND METHODS: A retrospective study was conducted in 69 consecutive cancer patients with solid tumors admitted to the ICU of a 400-bed general hospital in Greece, between October 2001 and October 2005. ...CONCLUSION: ECOG PS 3-4 prior to hospitalization was …
PATIENTS AND METHODS: A retrospective study was conducted in 69 consecutive cancer patients with solid tumors admitted to the ICU of …
Mild or moderate chronic obstructive pulmonary disease risk in elective coronary artery bypass grafting surgery.
Michalopoulos A, Geroulanos S, Papadimitriou L, Papadakis E, Triantafillou K, Papadopoulos K, Palatianos G. Michalopoulos A, et al. World J Surg. 2001 Dec;25(12):1507-11. doi: 10.1007/s00268-001-0161-x. World J Surg. 2001. PMID: 11775182
A history of chronic obstructive pulmonary disease (COPD) is considered a risk factor in patients undergoing coronary artery bypass grafting (CABG) surgery. ...We concluded that patients with a history of mild or moderate COPD undergoing elective CABG had mor
A history of chronic obstructive pulmonary disease (COPD) is considered a risk factor in patients undergoing coronary artery b
Systemic candidiasis in cardiac surgery patients.
Michalopoulos A, Kriaras J, Geroulanos S. Michalopoulos A, et al. Eur J Cardiothorac Surg. 1997 Apr;11(4):728-31. doi: 10.1016/s1010-7940(96)01071-8. Eur J Cardiothorac Surg. 1997. PMID: 9151045
The patients who developed systemic candidiasis had a median ICU and hospital stay of 58 and 60 days respectively. The mortality rate was 27.2%. ...Systemic candidiasis resulted in a significant prolongation of ICU and hospital length of stay, thus increasing extens …
The patients who developed systemic candidiasis had a median ICU and hospital stay of 58 and 60 days respectively. The mortality rate …
Determinants of hospital mortality after coronary artery bypass grafting.
Michalopoulos A, Tzelepis G, Dafni U, Geroulanos S. Michalopoulos A, et al. Chest. 1999 Jun;115(6):1598-603. doi: 10.1378/chest.115.6.1598. Chest. 1999. PMID: 10378555
METHODS: We prospectively collected various preoperative, operative, and immediate postoperative variables in a cohort of patients undergoing elective CABG surgery. RESULTS: Of the 2,014 consecutive patients (mean [+/- SD] age of 61.3+/-6.7 years old) undergoing elective C …
METHODS: We prospectively collected various preoperative, operative, and immediate postoperative variables in a cohort of patients un …
Change in anaesthesia practice and postoperative sedation shortens ICU and hospital length of stay following coronary artery bypass surgery.
Michalopoulos A, Nikolaides A, Antzaka C, Deliyanni M, Smirli A, Geroulanos S, Papadimitriou L. Michalopoulos A, et al. Respir Med. 1998 Aug;92(8):1066-70. doi: 10.1016/s0954-6111(98)90356-0. Respir Med. 1998. PMID: 9893777 Clinical Trial.
We randomized prospectively 144 patients, undergoing elective coronary artery bypass surgery, to either early or to routine extubation [mechanical ventilatory support for 4-7 h (Group A), or 8-14 h (Group B)]. ...Mechanical ventilatory support (mean +/- SD) was 6.3 +/- 0.7 …
We randomized prospectively 144 patients, undergoing elective coronary artery bypass surgery, to either early or to routine extubation [mech …
Severe sepsis in cardiac surgical patients.
Michalopoulos A, Stavridis G, Geroulanos S. Michalopoulos A, et al. Eur J Surg. 1998 Mar;164(3):217-22. doi: 10.1080/110241598750004670. Eur J Surg. 1998. PMID: 9562283
CONCLUSIONS: We concluded that severe sepsis mainly developed in cardiac surgery patients with serious operative and postoperative complications and was associated with a longer stay in both ICU and hospital, and a higher mortality....
CONCLUSIONS: We concluded that severe sepsis mainly developed in cardiac surgery patients with serious operative and postoperative complicat …
Antibiotic prophylaxis in cardiac surgery.
Kriaras I, Michalopoulos A, Michalis A, Palatianos G, Economopoulos G, Anagnostopoulos C, Geroulanos S. Kriaras I, et al. Among authors: michalopoulos a. J Cardiovasc Surg (Torino). 1997 Dec;38(6):605-10. J Cardiovasc Surg (Torino). 1997. PMID: 9461266 Clinical Trial.
METHODS: Cefuroxime received 501 patients (Group A), while a 4-day combination of amoxycillin-netilimicin 508 patients (Group B). ...CONCLUSIONS: A single shot of cefuroxime prophylaxis is equally effective and safe as a 4-day regimen with amoxycillin …
METHODS: Cefuroxime received 501 patients (Group A), while a 4-day combination of amoxycillin-netilimicin 508 patients (Group …
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