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584 results
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A specific and direct comparison of the trifluoromethyl and pentafluoro sulfanyl groups on the selective dopamine D(3) antagonist 3-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-1-phenyl-3-azabicyclo[3.1.0]hexane template.
Micheli F, Andreotti D, Braggio S, Checchia A. Micheli F, et al. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4566-8. doi: 10.1016/j.bmcl.2010.06.018. Epub 2010 Jun 8. Bioorg Med Chem Lett. 2010. PMID: 20573506
Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site.
Di Fabio R, Capelli AM, Conti N, Cugola A, Donati D, Feriani A, Gastaldi P, Gaviraghi G, Hewkin CT, Micheli F, Missio A, Mugnaini M, Pecunioso A, Quaglia AM, Ratti E, Rossi L, Tedesco G, Trist DG, Reggiani A. Di Fabio R, et al. Among authors: micheli f. J Med Chem. 1997 Mar 14;40(6):841-50. doi: 10.1021/jm960644a. J Med Chem. 1997. PMID: 9083472
2,3-Dihydro-6,7-dichloro-pyrido[2,3-b]pyrazine-8-oxide as selective glycine antagonist with in vivo activity.
Micheli F, Cugola A, Donati D, Missio A, Pecunioso A, Reggiani A, Tarzia G. Micheli F, et al. Bioorg Med Chem. 1997 Dec;5(12):2129-32. doi: 10.1016/s0968-0896(97)00156-9. Bioorg Med Chem. 1997. PMID: 9459010
New synthesis of substituted 2-carboxyindole derivatives: versatile introduction of a carbamoylethynyl moiety at the C-3 position.
Hewkin CT, Di Fabio R, Conti N, Cugola A, Gastaldi P, Micheli F, Quaglia AM. Hewkin CT, et al. Among authors: micheli f. Arch Pharm (Weinheim). 1999 Feb;332(2):55-8. doi: 10.1002/(sici)1521-4184(19993)332:2<55::aid-ardp55>3.0.co;2-z. Arch Pharm (Weinheim). 1999. PMID: 10191715
Studies on the novel anti-staphyloccal compound nematophin.
Kennedy G, Viziano M, Winders JA, Cavallini P, Gevi M, Micheli F, Rodegher P, Seneci P, Zumerle A. Kennedy G, et al. Among authors: micheli f. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1751-4. doi: 10.1016/s0960-894x(00)00331-0. Bioorg Med Chem Lett. 2000. PMID: 10937740
Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists.
Micheli F, Fabio RD, Cavanni P, Rimland JM, Capelli AM, Chiamulera C, Corsi M, Corti C, Donati D, Feriani A, Ferraguti F, Maffeis M, Missio A, Ratti E, Paio A, Pachera R, Quartaroli M, Reggiani A, Sabbatini FM, Trist DG, Ugolini A, Vitulli G. Micheli F, et al. Bioorg Med Chem. 2003 Jan 17;11(2):171-83. doi: 10.1016/s0968-0896(02)00424-8. Bioorg Med Chem. 2003. PMID: 12470711
2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: further characterization of 3,5-dimethyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester and structure-activity relationships.
Micheli F, Di Fabio R, Bordi F, Cavallini P, Cavanni P, Donati D, Faedo S, Maffeis M, Sabbatini FM, Tarzia G, Tranquillini ME. Micheli F, et al. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2113-8. doi: 10.1016/s0960-894x(03)00396-2. Bioorg Med Chem Lett. 2003. PMID: 12798316
Benzoazepine derivative as potent antagonists of the glycine binding site associated to the NMDA receptor.
Di Fabio R, Micheli F, Baraldi D, Bertani B, Conti N, Dal Forno G, Feriani A, Donati D, Marchioro C, Messeri T, Missio A, Pasquarello A, Pentassuglia G, Pizzi DA, Provera S, Quaglia AM, Sabbatini FM. Di Fabio R, et al. Among authors: micheli f. Farmaco. 2003 Sep;58(9):723-38. doi: 10.1016/S0014-827X(03)00166-6. Farmaco. 2003. PMID: 13679166
Enantiomerically pure tetrahydroquinoline derivatives as in vivo potent antagonists of the glycine binding site associated to the NMDA receptor.
Di Fabio R, Tranquillini E, Bertani B, Alvaro G, Micheli F, Sabbatini F, Pizzi MD, Pentassuglia G, Pasquarello A, Messeri T, Donati D, Ratti E, Arban R, Dal Forno G, Reggiani A, Barnaby RJ. Di Fabio R, et al. Among authors: micheli f. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3863-6. doi: 10.1016/j.bmcl.2003.06.001. Bioorg Med Chem Lett. 2003. PMID: 14552796
3-Methyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester: an exploration of the C-2 position. Part II, A solid-phase approach.
Micheli F, Di Fabio R, Cavallini P, Cavanni P, Donati D, Hamdan M, Maria Sabbatini F, Messeri T. Micheli F, et al. Farmaco. 2004 Feb;59(2):119-23. doi: 10.1016/j.farmac.2003.12.006. Farmaco. 2004. PMID: 14871503
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