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M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice.
Seth RK, Das S, Pourhoseini S, Dattaroy D, Igwe S, Ray JB, Fan D, Michelotti GA, Diehl AM, Chatterjee S. Seth RK, et al. Among authors: michelotti ga. J Pharmacol Exp Ther. 2015 Jan;352(1):77-89. doi: 10.1124/jpet.114.218131. Epub 2014 Oct 27. J Pharmacol Exp Ther. 2015. PMID: 25347994 Free PMC article.
Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation.
Dattaroy D, Seth RK, Das S, Alhasson F, Chandrashekaran V, Michelotti G, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Dattaroy D, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G510-25. doi: 10.1152/ajpgi.00259.2015. Epub 2015 Dec 30. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26718771 Free PMC article.
TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.
Seth RK, Das S, Dattaroy D, Chandrashekaran V, Alhasson F, Michelotti G, Nagarkatti M, Nagarkatti P, Diehl AM, Bell PD, Liedtke W, Chatterjee S. Seth RK, et al. Free Radic Biol Med. 2017 Jan;102:260-273. doi: 10.1016/j.freeradbiomed.2016.11.047. Epub 2016 Nov 29. Free Radic Biol Med. 2017. PMID: 27913210 Free PMC article.
Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.
Dattaroy D, Pourhoseini S, Das S, Alhasson F, Seth RK, Nagarkatti M, Michelotti GA, Diehl AM, Chatterjee S. Dattaroy D, et al. Among authors: michelotti ga. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G298-312. doi: 10.1152/ajpgi.00346.2014. Epub 2014 Dec 11. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25501551 Free PMC article.
NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.
Das S, Alhasson F, Dattaroy D, Pourhoseini S, Seth RK, Nagarkatti M, Nagarkatti PS, Michelotti GA, Diehl AM, Kalyanaraman B, Chatterjee S. Das S, et al. Among authors: michelotti ga. Am J Pathol. 2015 Jul;185(7):1944-57. doi: 10.1016/j.ajpath.2015.03.024. Epub 2015 May 16. Am J Pathol. 2015. PMID: 25989356 Free PMC article.
87 results