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Type 1 diabetes.
Atkinson MA, Eisenbarth GS, Michels AW. Atkinson MA, et al. Lancet. 2014 Jan 4;383(9911):69-82. doi: 10.1016/S0140-6736(13)60591-7. Epub 2013 Jul 26. Lancet. 2014. PMID: 23890997 Free PMC article. Review.
The anti-insulin trimolecular complex in type 1 diabetes.
Michels AW, Nakayama M. Michels AW, et al. Curr Opin Endocrinol Diabetes Obes. 2010 Aug;17(4):329-34. doi: 10.1097/MED.0b013e32833aba41. Curr Opin Endocrinol Diabetes Obes. 2010. PMID: 20489610 Free PMC article. Review.
2011 Update: antigen-specific therapy in type 1 diabetes.
Michels AW, von Herrath M. Michels AW, et al. Curr Opin Endocrinol Diabetes Obes. 2011 Aug;18(4):235-40. doi: 10.1097/MED.0b013e32834803ae. Curr Opin Endocrinol Diabetes Obes. 2011. PMID: 21844706 Free PMC article. Review.
Immune intervention in type 1 diabetes.
Michels AW, Eisenbarth GS. Michels AW, et al. Semin Immunol. 2011 Jun;23(3):214-9. doi: 10.1016/j.smim.2011.07.003. Epub 2011 Aug 17. Semin Immunol. 2011. PMID: 21852151 Free PMC article. Review.
Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.
Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Crawford F, et al. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16729-34. doi: 10.1073/pnas.1113954108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949373 Free PMC article.
Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation.
Michels AW, Ostrov DA, Zhang L, Nakayama M, Fuse M, McDaniel K, Roep BO, Gottlieb PA, Atkinson MA, Eisenbarth GS. Michels AW, et al. J Immunol. 2011 Dec 1;187(11):5921-30. doi: 10.4049/jimmunol.1100746. Epub 2011 Oct 31. J Immunol. 2011. PMID: 22043012 Free PMC article.
Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice.
Zhang L, Stadinski BD, Michels A, Kappler JW, Eisenbarth GS. Zhang L, et al. Diabetes Metab Res Rev. 2011 Nov;27(8):784-9. doi: 10.1002/dmrr.1252. Diabetes Metab Res Rev. 2011. PMID: 22069260
Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial.
Herold KC, Gitelman SE, Willi SM, Gottlieb PA, Waldron-Lynch F, Devine L, Sherr J, Rosenthal SM, Adi S, Jalaludin MY, Michels AW, Dziura J, Bluestone JA. Herold KC, et al. Diabetologia. 2013 Feb;56(2):391-400. doi: 10.1007/s00125-012-2753-4. Epub 2012 Oct 21. Diabetologia. 2013. PMID: 23086558 Free PMC article. Clinical Trial.
Targeting the trimolecular complex.
Michels AW. Michels AW. Clin Immunol. 2013 Dec;149(3):339-44. doi: 10.1016/j.clim.2013.02.020. Epub 2013 Mar 5. Clin Immunol. 2013. PMID: 23537861 Free PMC article. Review.
Targeting the trimolecular complex: the pathway towards type 1 diabetes prevention.
Michels AW. Michels AW. Diabetes Technol Ther. 2013 Jun;15 Suppl 2(Suppl 2):S2-8-S2-12. doi: 10.1089/dia.2013.0114. Diabetes Technol Ther. 2013. PMID: 23786298 Free PMC article.
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