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Measuring antiplatelet drug effects in the laboratory.
Harrison P, Frelinger AL 3rd, Furman MI, Michelson AD. Harrison P, et al. Thromb Res. 2007;120(3):323-36. doi: 10.1016/j.thromres.2006.11.012. Epub 2007 Jan 17. Thromb Res. 2007. PMID: 17239428 Review.
Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis.
Gremmel T, Yanachkov IB, Yanachkova MI, Wright GE, Wider J, Undyala VV, Michelson AD, Frelinger AL 3rd, Przyklenk K. Gremmel T, et al. Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):501-9. doi: 10.1161/ATVBAHA.115.306885. Epub 2016 Jan 7. Arterioscler Thromb Vasc Biol. 2016. PMID: 26743169 Free PMC article.
How I use laboratory monitoring of antiplatelet therapy.
Michelson AD, Bhatt DL. Michelson AD, et al. Blood. 2017 Aug 10;130(6):713-721. doi: 10.1182/blood-2017-03-742338. Epub 2017 Jun 9. Blood. 2017. PMID: 28600334 Review.
Novel aspects of antiplatelet therapy in cardiovascular disease.
Gremmel T, Michelson AD, Frelinger AL III, Bhatt DL. Gremmel T, et al. Res Pract Thromb Haemost. 2018 May 27;2(3):439-449. doi: 10.1002/rth2.12115. eCollection 2018 Jul. Res Pract Thromb Haemost. 2018. PMID: 30046748 Free PMC article. Review.
Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization.
Gremmel T, Frelinger AL 3rd, Michelson AD. Gremmel T, et al. PLoS One. 2015 Aug 3;10(8):e0134599. doi: 10.1371/journal.pone.0134599. eCollection 2015. PLoS One. 2015. PMID: 26237513 Free PMC article.
Diabetes mellitus, CYP2C19 genotype, and response to escalating doses of clopidogrel. Insights from the ELEVATE-TIMI 56 Trial.
Carreras ET, Hochholzer W, Frelinger AL 3rd, Nordio F, O'Donoghue ML, Wiviott SD, Angiolillo DJ, Michelson AD, Sabatine MS, Mega JL. Carreras ET, et al. Thromb Haemost. 2016 Jul 4;116(1):69-77. doi: 10.1160/TH15-12-0981. Epub 2016 Mar 24. Thromb Haemost. 2016. PMID: 27009617 Clinical Trial.
Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel. Results from PRINCIPLE-TIMI 44.
Frelinger AL 3rd, Michelson AD, Wiviott SD, Trenk D, Neumann FJ, Miller DL, Jakubowski JA, Costigan TM, McCabe CH, Antman EM, Braunwald E. Frelinger AL 3rd, et al. Thromb Haemost. 2011 Aug;106(2):219-26. doi: 10.1160/TH11-03-0185. Epub 2011 Jun 28. Thromb Haemost. 2011. PMID: 21713327 Clinical Trial.
Antiplatelet therapy in children.
Israels SJ, Michelson AD. Israels SJ, et al. Thromb Res. 2006;118(1):75-83. doi: 10.1016/j.thromres.2004.12.016. Epub 2005 Feb 1. Thromb Res. 2006. PMID: 16709476 Review.
Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention.
Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Braunwald E, et al. Clin Cardiol. 2008 Mar;31(3 Suppl 1):I28-35. doi: 10.1002/clc.20359. Clin Cardiol. 2008. PMID: 18481820 Free PMC article. Review.
Investigating the mechanisms of hyporesponse to antiplatelet approaches.
Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Braunwald E, et al. Clin Cardiol. 2008 Mar;31(3 Suppl 1):I21-7. doi: 10.1002/clc.20360. Clin Cardiol. 2008. PMID: 18481819 Free PMC article. Review.
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