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Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization.
Frelinger AL 3rd, Li Y, Linden MD, Barnard MR, Fox ML, Christie DJ, Furman MI, Michelson AD. Frelinger AL 3rd, et al. Among authors: michelson ad. Circulation. 2009 Dec 22;120(25):2586-96. doi: 10.1161/CIRCULATIONAHA.109.900589. Epub 2009 Dec 7. Circulation. 2009. PMID: 19996015
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Frelinger AL 3rd, Furman MI, Linden MD, Li Y, Fox ML, Barnard MR, Michelson AD. Frelinger AL 3rd, et al. Among authors: michelson ad. Circulation. 2006 Jun 27;113(25):2888-96. doi: 10.1161/CIRCULATIONAHA.105.596627. Epub 2006 Jun 19. Circulation. 2006. PMID: 16785341
The Platelet Activity After Clopidogrel Termination (PACT) study.
Frelinger AL 3rd, Barnard MR, Fox ML, Michelson AD. Frelinger AL 3rd, et al. Among authors: michelson ad. Circ Cardiovasc Interv. 2010 Oct;3(5):442-9. doi: 10.1161/CIRCINTERVENTIONS.110.937961. Epub 2010 Aug 24. Circ Cardiovasc Interv. 2010. PMID: 20736449 Clinical Trial.
Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function.
Frelinger AL 3rd, Bhatt DL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Lampa M, Brooks JK, Barnard MR, Michelson AD. Frelinger AL 3rd, et al. Among authors: michelson ad. J Am Coll Cardiol. 2013 Feb 26;61(8):872-9. doi: 10.1016/j.jacc.2012.11.040. Epub 2013 Jan 16. J Am Coll Cardiol. 2013. PMID: 23333143 Free article. Clinical Trial.
Platelet activation and inhibition in sickle cell disease (pains) study.
Frelinger AL 3rd, Jakubowski JA, Brooks JK, Carmichael SL, Berny-Lang MA, Barnard MR, Heeney MM, Michelson AD. Frelinger AL 3rd, et al. Among authors: michelson ad. Platelets. 2014;25(1):27-35. doi: 10.3109/09537104.2013.770136. Epub 2013 Mar 7. Platelets. 2014. PMID: 23469943
244 results