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135 results
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Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer.
Paulsson J, Sjöblom T, Micke P, Pontén F, Landberg G, Heldin CH, Bergh J, Brennan DJ, Jirström K, Ostman A. Paulsson J, et al. Am J Pathol. 2009 Jul;175(1):334-41. doi: 10.2353/ajpath.2009.081030. Epub 2009 Jun 4. Am J Pathol. 2009. PMID: 19498003 Free PMC article.
A novel strategy based on histological protein profiling in-silico for identifying potential biomarkers in urinary bladder cancer.
Segersten MU, Edlund EK, Micke P, de la Torre M, Hamberg H, Edvinsson AE, Andersson SE, Malmström PU, Wester HK. Segersten MU, et al. BJU Int. 2009 Dec;104(11):1780-5. doi: 10.1111/j.1464-410X.2009.08674.x. Epub 2009 Jun 12. BJU Int. 2009. PMID: 19522865

Expression patterns for seven proteins were significantly altered (P < 0.05) with higher stage and/or grade. Three of those (CN130, DSG3, PHF6) lack characterization in bladder cancer, whereas the remaining four proteins have previously been suggested as key proteins/po

Expression patterns for seven proteins were significantly altered (P < 0.05) with higher stage and/or grade. Three of those (CN130

Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.
Göransson H, Edlund K, Rydåker M, Rasmussen M, Winquist J, Ekman S, Bergqvist M, Thomas A, Lambe M, Rosenquist R, Holmberg L, Micke P, Botling J, Isaksson A. Göransson H, et al. PLoS One. 2009 Jun 26;4(6):e6057. doi: 10.1371/journal.pone.0006057. PLoS One. 2009. PMID: 19557126 Free PMC article.
Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.
Micke P, Edlund K, Holmberg L, Kultima HG, Mansouri L, Ekman S, Bergqvist M, Scheibenflug L, Lamberg K, Myrdal G, Berglund A, Andersson A, Lambe M, Nyberg F, Thomas A, Isaksson A, Botling J. Micke P, et al. J Thorac Oncol. 2011 Nov;6(11):1833-40. doi: 10.1097/JTO.0b013e3182295917. J Thorac Oncol. 2011. PMID: 22011649
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P. Edlund K, et al. Int J Cancer. 2012 Nov 15;131(10):2264-73. doi: 10.1002/ijc.27518. Epub 2012 Apr 24. Int J Cancer. 2012. PMID: 22392539
Higher stromal expression of CD99 was associated with better prognosis in the univariate (p = 0.037) and multivariate (p = 0.039) analysis. ...The prognostic impact of stromal CD99 protein expression was confirmed in an independent cohort of 240 NSCLC patients (p
Higher stromal expression of CD99 was associated with better prognosis in the univariate (p = 0.037) and multivariate (p = 0.0 …
Consistent mutation status within histologically heterogeneous lung cancer lesions.
Mattsson JS, Imgenberg-Kreuz J, Edlund K, Botling J, Micke P. Mattsson JS, et al. Histopathology. 2012 Oct;61(4):744-8. doi: 10.1111/j.1365-2559.2012.04245.x. Histopathology. 2012. PMID: 22458769
Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors.
Edlund K, Larsson O, Ameur A, Bunikis I, Gyllensten U, Leroy B, Sundström M, Micke P, Botling J, Soussi T. Edlund K, et al. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9551-6. doi: 10.1073/pnas.1200019109. Epub 2012 May 24. Proc Natl Acad Sci U S A. 2012. PMID: 22628563 Free PMC article.
Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation.
Botling J, Edlund K, Lohr M, Hellwig B, Holmberg L, Lambe M, Berglund A, Ekman S, Bergqvist M, Pontén F, König A, Fernandes O, Karlsson M, Helenius G, Karlsson C, Rahnenführer J, Hengstler JG, Micke P. Botling J, et al. Clin Cancer Res. 2013 Jan 1;19(1):194-204. doi: 10.1158/1078-0432.CCR-12-1139. Epub 2012 Oct 2. Clin Cancer Res. 2013. PMID: 23032747

The top 450 probe sets identified using a univariate Cox regression model (significance level P < 0.01) were tested in a meta-analysis including five publicly available independent lung cancer cohorts (n = 860). RESULTS: The meta-analysis revealed 14 genes that were sig

The top 450 probe sets identified using a univariate Cox regression model (significance level P < 0.01) were tested in a meta-anal

A systematic analysis of commonly used antibodies in cancer diagnostics.
Gremel G, Bergman J, Djureinovic D, Edqvist PH, Maindad V, Bharambe BM, Khan WA, Navani S, Elebro J, Jirström K, Hellberg D, Uhlén M, Micke P, Pontén F. Gremel G, et al. Histopathology. 2014 Jan;64(2):293-305. doi: 10.1111/his.12255. Epub 2013 Nov 5. Histopathology. 2014. PMID: 24330150
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