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The Genetics of Primary Microcephaly.
Jayaraman D, Bae BI, Walsh CA. Jayaraman D, et al. Annu Rev Genomics Hum Genet. 2018 Aug 31;19:177-200. doi: 10.1146/annurev-genom-083117-021441. Epub 2018 May 23. Annu Rev Genomics Hum Genet. 2018. PMID: 29799801 Review.
Primary microcephaly (MCPH, for "microcephaly primary hereditary") is a disorder of brain development that results in a head circumference more than 3 standard deviations below the mean for age and gender. It has a wide variety of causes, including tox …
Primary microcephaly (MCPH, for "microcephaly primary hereditary") is a disorder of brain development that resul …
Consequences of Centrosome Dysfunction During Brain Development.
Nano M, Basto R. Nano M, et al. Adv Exp Med Biol. 2017;1002:19-45. doi: 10.1007/978-3-319-57127-0_2. Adv Exp Med Biol. 2017. PMID: 28600781 Review.
As one of the most structurally complex organs in our body, the brain is particularly susceptible to centrosome dysfunction. Autosomal recessive primary microcephaly (MCPH), primordial dwarfism disease Seckel syndrome (SCKS) and microcephalic osteodysp …
As one of the most structurally complex organs in our body, the brain is particularly susceptible to centrosome dysfunction. Autosomal …
Prophasing interphase chromatin for assessing genetic damages-The evolution, applications and the future prospects.
Ravi M, Lal AS, Begum SK. Ravi M, et al. Mutat Res. 2018 Jul;810:19-32. doi: 10.1016/j.mrfmmm.2018.06.001. Epub 2018 Jun 8. Mutat Res. 2018. PMID: 29906650 Review.
Initial experiments on PCC were reported in late 1960s and the technique has evolved into one with wide range of applications owing to its increased efficiency in detecting primary DNA damages. Biodosimetry remains as the primary area which utilizes PCC technique to …
Initial experiments on PCC were reported in late 1960s and the technique has evolved into one with wide range of applications owing to its i …